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颅脑弥漫性轴索损伤的临床诊治与预后分析 被引量:6

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摘要 弥漫性轴索损伤(DAI )是在颅脑外伤患者详细病理解剖时发现的一种病理变化,其研究最早可追溯至上世纪70年代末,1977年Adams等[1]多次报道这种脑损伤死亡的脑病理表现,并于1982年将其命名为DAI。研究[2]表明因头部受减速惯性力或(和)成角加速所造成的颅脑损伤会导致DAI ,主要特征为广泛神经元轴索断裂,因病情较严重,且病理学上具有一定的特殊性,其植物及重残生存率达到30%~40%,死亡率高达42%~62%,从而使患者、家庭及社会承受着较大的压力和负担。脑弥漫性轴索损伤(DAI )也称之为外脑性轴索损伤(TAI ),其发生与外脑性损伤(TBI)有着密切的关系。因外脑性损伤(TBI)所引起的脑弥漫性轴索损伤(DAI )的发病率和死亡率至少占35%,而不会发生占位损伤[3]。当前,临床治疗DAI 仍无特效药物及相关措施。本研究中作者对65例颅脑DAI患者的临床资料进行回顾性分析,对DAI的临床诊治措施和预后进行探讨,现报告如下。
出处 《实用临床医药杂志》 CAS 2014年第17期152-154,共3页 Journal of Clinical Medicine in Practice
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参考文献11

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二级参考文献15

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