摘要
纳米复合水凝胶(NC-Gels)因兼具有机相及无机相的优点,且具有独特的结构特征和理化性能,近年来已成为水凝胶领域的研究重点,在智能器件、生物医药、组织工程等领域有着广泛的应用前景.基于有机/无机杂化原理,通过交联点的结构与功能性设计和凝胶网络的可控构筑,获得了一系列力学性能优异并具有多重响应甚至智能化响应的NC-Gels,并提出了以有机微球或功能化杂化微球分别为交联点构建纳米复合水凝胶(OC-Gels)和杂化水凝胶(H-Gels)的新方法,探索了其在生物医学和智能传感领域等的初步应用.
Nanocomposite hybrid hydrogels（NC-Gels） are a topic of intense interest at present because they combine the advantages of the organic component and the inorganic component into one material. The NC-Gels offer prospects for application in diverse fields including mechanical device,drug delivery,tissue engineering,etc. We have been focusing on constructing NC-Gels with tailored functionalities by controlling over the crosslinking agents,polymer components and hydrogel network structure. A series of NC-Gels were developed with surprising mechanical properties,multiple functionalities and even smart sensitivity. More recently,a facile approach was proposed to fabricate organic cross-linked hydrogels（OC-Gels） and hybrid hydrogels（H-Gels）by using photoactive polystyrene（ PS） nanoparticles and functional hybrid particles（ H-Gels） as the crosslinking agents,respectively,which provides a platform in building up complex systems for the smart hydrogels.The applications of these hydrogels were also explored in area of the biomedical and smart sensor.
出处
《高分子学报》
SCIE
CAS
CSCD
北大核心
2014年第10期1342-1349,共8页
Acta Polymerica Sinica
基金
国家自然科学基金杰出青年基金(基金号50925312)
长江学者和创新团队发展计划(项目号T2011079
IRT1221)资助
关键词
有机/无机杂化
纳米复合水凝胶
高强度
功能化
多重智能响应
Organic /inorganic hybrid
Nanocomposite hydrogels
High mechanical properties
Functionalities
Multi-responsiveness
