摘要
目的：分析新疆心脑血管病医院（简称“我院”）降钙素原（PCT）监测现状,研究 PCT 监测流程,指导临床抗菌药物合理应用。方法实时监测我院2013-04-18-2013-10-18住院患者血清 PCT 值,并跟踪每一位检测PCT患者的抗菌药物使用情况。结果共对262人（同一患者转科只计一人）进行了PCT监测,其中89.4%的患者只检测了1次,10.6%的患者作了2次或2次以上检测；血清PCT〈0.1 ng·mL-1的患者有49.4%使用了抗菌药物,PCT≥0.1 ng·mL-1的患者有94.9%使用了抗菌药物；外科手术患者PCT监测率为19.25%,使用抗菌药物的占99.2%；心内科介入手术及非手术患者共监测222次,其中使用抗菌药物的占78.4%。结论我院PCT送检次数、送检时间不科学,缺乏连续检测,缺少对 PCT 值的动态观察,未体现出PCT指导临床抗菌药物合理使用的作用。
Objective To analyze the status of monitoring of procalcitonin （PCT）in our hospital （Xinjiang Hospital of Cardio-cerebrovascular Diseases ）, study the PCT monitoring process of procalcitonin and guide clinical rational use of antibacterial drugs. Methods Real time monitoring was conducted for serum PCT values of hospitalized patients from April 18 to October 18, 2013, and antibacterial drug use of each patient with PCT detected was tracked.Results A total of 262 people （the same patient who was referred to other departments was calculated as one）received PCT monitoring, 89.4% of the patients were tested only 1 time,10.6% of the patients received PCT test for 2 times or more.Among patients whose serum PCT〈0.1 ng · mL-1 ,49.4% of them used antibacterial drugs;among patients with PCT≥0.1 ng·mL-1 ,94.9% of them used antibacterial drugs.The PCT monitoring rate in surgical patients was 19.25%,99.2% of whom used antibacterial drugs.The PCT monitoring was performed 222 times for patients both with invasive surgery and without surgery in the department of cardiology,among whom 78.4% patients who used antibacterial drugs.Conclusion Delivering frequency and delivering time of PCT samples were unscientific in our hospital with lack of continuous testing and dynamic observation of PCT values, which made PCT inefficient on guiding clinical rational use of antibacterial drugs.
出处
《中国药事》
CAS
2014年第9期1029-1033,共5页
Chinese Pharmaceutical Affairs
关键词
生物标记物监测
降钙素原
PCT监测流程
抗菌药物
临床合理用药
biomarker monitoring
procalcitonin （PCT）
PCT monitoring process
antibacterialdrugs
clinical rational drug use
