摘要
肿瘤严重威胁人类健康,复发转移是导致其不良预后的重要原因,缺乏有效防治措施。从中医病机来看,肿瘤与中医"痰"存在密切联系。化痰药是中医临床治疗肿瘤常用的中药种类,而现代药理学研究也不断揭示出化痰药中有许多抗癌活性成分。文章综述了化痰中药在对肿瘤细胞本身、癌周微环境、宿主内环境几个方面的作用机制,为从痰论治肿瘤的复发转移提供了依据。
Tumor is a serious threat to human health, the recurrence and metastasis of tumor are the main reasons for bad prognosis, and there are no effective measures for prevention and treatment. According to the TCM pathogenesis, tumor is closely related to ＇phlegm＇, and phlegm-dispelling herbs constitute a category of commonly medicine in the TCM treatment of tumor, the pharmacological researches reveal that there are many anti-carcinogens in these herbs. This article reviews the mechanisms of phlegm-dispelling herbs on tumor cell itself, tumor microenvironment and hosting intemal environment. It provides a basis for preventing tumor recurrence and metastasis based on the theory of phlegm.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2014年第9期2886-2889,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
上海市中医药事业发展三年行动计划(No.ZYSNXD-CC-ZDYJ024
No.ZYSNXD-CC-MZY054)
上海市卫生局课题(No.2010QL049A
No.2011ZX009)~~
关键词
肿瘤
复发
转移
化痰药
中医药
Tumor
Recurrence
Metastasis
Phlegm-dispelling herbs
Traditional Chinese medicine
