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鼠神经生长因子在外伤性面神经麻痹患者中的应用价值探讨 被引量:6

Application value of mouse nerve growth factor in traumatic facial paralysis patients
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摘要 目的探讨分析鼠神经生长因子在外伤性面神经麻痹患者中的应用价值。方法以我院2010年8月至2013年8月间,收治的50例外伤性面神经麻痹患者为研究对象,随机分为观察组与对照组,所有患者均予以抗感染、激素、维生素B1、维生素B12、能量合剂辅助以理疗等常规治疗及表情肌功能训练等按摩护理,观察组患者在此基础予以鼠神经生长因子治疗,比较两组患者之间的差异。结果观察组治疗后总有效率92.0%优于对照组68.0%,其差异有统计学意义(χ2=4.88,P<0.05);观察组治疗后House-Brackmann面神经功能评价分级情况优于对照组患者,Ⅰ级(χ2=8.04)、Ⅲ级(χ2=5.37)、Ⅳ级以上(χ2=4.15),其差异有统计学意义(P<0.05)。结论鼠神经生长因子在外伤性面神经麻痹患者中应用,提高患者治疗疗效,缓解了患者的症状,促进患者健康恢复,具有临床推广价值。 Objective To investigate and analyse the application value of mouse nerve growth factor in traumatic facial paralysis patients. Methods 50 cases of traumatic facial paralysis patients those who were treated in our hospital during August 2010 and August 2013 were selected as the study object, they were randomly divided into observation group and control group. All patients were given the treatment including anti infection, hormone, vitamin B1, vitamin B12, energy mixture with physiotherapy, other conventional treatments, facial muscle function training and massage care, patients the observation group were given mouse nerve growth factor additionally, compared the differences between the two groups. Results After the treatment, total efficiency of the observation group ( 92% ) was higher than that of control group ( 68% ) , the difference was statistically signifieant ( X2 = 4.88, P 〈 0. 05 ). House - Brackmann score of facial nerve function of observation group were better than control group patients, Ⅰ level (X2 =8. 04) , Ⅲ level (X2 = 5.37), Ⅳ level and above (X2 = 4.15), the differences were statistically significant (P 〈 0. 05). Conclusions The application of mouse nerve growth factor in traumatic facial paralysis patients can improve treatment efficacy, alleviate the symptoms, promote health recovery, worth of clinical expansion.
作者 谭兴实
出处 《齐齐哈尔医学院学报》 2014年第17期2497-2498,共2页 Journal of Qiqihar Medical University
关键词 鼠神经生长因子 外伤性面神经麻痹 House-Brackmann面神经分级 Nerve growth factor Traumatic facial paralysis House - Brackmann facial nerve grading.
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