摘要
目的 探讨不同分期乳腺癌的手术治疗方法及综合治疗效果。方法 80例乳腺癌患者依据其临床分期、肿瘤大小等采用不同手术方式治疗,其中4例Ⅰ期乳腺癌患者行保乳乳腺癌切除术,20例Ⅱ~Ⅲ期乳腺癌伴腋窝1、2组淋巴结肿大者行乳腺癌改良根治术,49例伴腋窝1、2、3组淋巴结肿大者行乳腺癌根治术,1例Ⅲc期及6例Ⅳ期患者行姑息性全乳房切除术。术后除Ⅰ期4例外,均行化、放疗等辅助治疗。随访5a观察存活率。结果 4例行保乳乳腺癌切除术者均存活;20例行乳腺癌改良根治术者存活10例,生存率50.00%;49例行乳腺癌根治术者存活41例,生存率83.67%;7例行姑息性全乳房切除术者存活2例,生存率28.57%。60例肿瘤直径〈3cm者术后5a生存率（86.67%）高于20例直径〉3cm者（25.00%）（P〈0.05）。结论 Ⅱ期以上乳腺癌患者行乳腺癌根治术和改良乳腺癌根治术,术后辅助放、化疗,可提高患者5a生存率。
Objective To explore the surgical treatment and results of comprehensive treatment of breast cancer in different stages. Methods Eighty patients with breast cancer were performed operations according to clinical staging and tumor size. In 80 patients with breast cancer, 4 in stage I were performed simple mastectomy, 20 in stage Ⅱ to Ⅲ complicated with group 1 and 2 axillary lymphadenectasis modified radical mastectomy and 49 in stage Ⅱ to Ⅱ complicated with group 1, 2 and 3 axillary lymphadeneetasis were respectively performed radical mastectomy, and 1 of stage Ⅲ c and 6 of stage Ⅳ underwent palliative total mastectomy. Seventy-six patients received chemotherapy or radiotherapy after operation except 4 patients in stage l . All patients were followed up for 5 years to observe the survival rate. Results Four patients survived after simple mastectomy. In 20 patients receiving modified radical mastectomy, 10 survived （50.00 % ）. In 49 patients receiving radical mastectomy, 41 survived （83.67 %）. In 7 patients receiving palliative breast cancer resection, 2 survived （28.57%）. The 5-year survival rate in 60 patients with tumor diameter 〈3 cm was 86.67%, higher than that in 20 patients with tumor diameter 〉 3 cm （25.00 %） （P〈0.05）. Conclusion For patients with breast cancer in stage Ⅱ and over, radical mastectomy or modified radical mastectomy plus adjuvant radiotherapy or chemotherapy can improve the 5-year survival rate.
出处
《中华实用诊断与治疗杂志》
2014年第9期884-885,共2页
Journal of Chinese Practical Diagnosis and Therapy
关键词
乳腺癌
手术
生存率
Breast cancer
operation
survival rate
