摘要
目的建立健骨口服液的质量控制方法。方法采用TLC法对健骨口服液中淫羊藿、黄芪、补骨脂进行定性鉴别;用HPLC法测定口服液中淫羊藿苷的含量。结果薄层色谱中斑点清晰,易于识别;HPLC法精密度、重复性良好。淫羊藿苷对照品在42.0-210.0μg·ml-1,r=0.9993范围内呈良好的线性关系,平均加样回收率为98.15%,RSD为1.18%。结论本法可有效地控制健骨口服液的质量。
Objective To establish a quality standard forJianguliquid. Methods TLC was used for identification of radix astragali and psoralea fruits while HPLC was used for quantitative determination of icariin. Results The picture of Epimedii Folium TLC was clear and negative control had no interference. The sample of chlorogenic acid showed a good linear relationship（ r = 0. 9993） in the range of 42. 0- 210. 0 μg·ml- 1. The average recovery was 98. 15%,RSD 1. 18%. Conclusion This method can be used for quality control of Jiangu liquid.
出处
《解放军药学学报》
CAS
2014年第4期348-351,共4页
Pharmaceutical Journal of Chinese People's Liberation Army
