摘要
目的:考察人参新炮制品黑参抗血栓药理作用。方法:观察黑参对急性血瘀模型大鼠血液流变性的影响;对大鼠实验性血栓形成的影响;对小鼠出凝血时间的影响;对小鼠耳廓微循环的影响。结果:黑参能明显降低急性血瘀模型大鼠全血黏度、红细胞聚集指数和卡松黏度,能够减轻大鼠血栓湿重,加快小鼠耳廓毛细血管血流速度,延长小鼠的出血及凝血时间。结论:人参新炮制品黑参具有改善血液流变学、改善微循环、抑制血栓形成、抗凝血及镇痛作用。
Objective： To investigate the antithrombotic effect of black ginseng. Method： To observe the effects on the hemorheology of black ginseng in acute blood stasis rats ; effects on experimental thrombus formation in rats; the effects on clotting time and auricle microcireulation in mice. Result： Black ginseng can decrease the whole blood viscosity induced by adrenaline and ice water stimulation; can reduce the erythrocyte electrophoresis time, Casson viscosity, erythrocyte aggregation index, wet weight of thrombus in rats ; can speed up the auricle capillary blood flow velocity, and also can prolong the bleeding and clotting time. Conclusion ： Black ginseng has the effect of improving hemorheology and microcirculation, inhibiting thrombosis, also has the effect of anticoagulant and analgesic.
出处
《辽宁中医药大学学报》
CAS
2014年第9期45-46,共2页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家十一五科技支撑计划课题(2011B15B23)
广东省创新团队课题(2010T117)
关键词
黑参
抗血栓
实验研究
black ginseng
antithrombotic effect
experimental study
