滤泡树突细胞肉瘤序贯发生弥漫大B细胞淋巴瘤:1例报道及机制探讨
Sequential development of follicular dendritic cell sarcoma to diffuse large B-cell lymphoma: one case report and discussion on its possible mechanism
摘要
本文报道1例在滤泡树突细胞肉瘤基础上序贯发生弥漫大B细胞淋巴瘤的罕见病例,并由此探讨滤泡树突细胞肉瘤在弥漫大B细胞淋巴瘤发生和发展中的可能作用。推测肿瘤组织微环境变化及肿瘤细胞转分化可能是这种肿瘤转化发生的两种重要机制。
This article reports a rare case of sequential development of follicular dendritic cell sarcoma (FDCS) to diffuse large B-cell lymphoma (DLBCL), and discusses the possible role of FDCS in facilitatinging genesis and development of DLBCL. It suggests that tumor microenvironment variation and transdifferentiation of tumor cells may be the two important mechanisms for this sequential development.
出处
《肿瘤》
CAS
CSCD
北大核心
2014年第8期768-770,共3页
Tumor
关键词
树突状细胞肉瘤
滤泡
淋巴瘤
大B细胞
弥漫性
细胞转分化
肿瘤微环境
Dendritic cell sarcoma, follicular
Lymphoma, large B-cell, diffuse
Celltransdifferentiation
Tumor microenvironment
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