摘要
长期给予维生素K拮抗剂抗凝治疗的患者在行外科手术或行有创性操作时面临着出血风险,而在围术期停用维生素K拮抗剂又可能增加血栓栓塞风险。使用治疗剂量肝素类药物的桥接抗凝治疗后可避免围术期暂时中断维生素K拮抗剂治疗所致的血栓栓塞事件。本文对此进行有关讨论。
Patients receiving long-term anticoagulation therapy of vitamin K antagonist (VKA) may face risk of bleeding when receive surgery or invasive operation, and perioperative interruption of VKA may Increase risk of thromboembolism. Bridging anticoagulation therapy with therapeutic dose of heparin group drugs may avoid throm- boembolic events induced by temporary interruption of VKA therapy during perioperative period, This article made a relative discussion.
出处
《心血管康复医学杂志》
CAS
2014年第4期472-474,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
抗凝药
肝素
低分子量
维生素K
Anticoagulants
Heparin, low-molecular-weight
Vitamin K