摘要
该文收集中国期刊全文数据库(CNKI)中中医药治疗骨质疏松症、骨性关节炎的文献,并对文献报道的方剂进行筛选、规范后,建立相应方剂数据库,运用中医传承辅助平台软件挖掘分析其中的用药规律。筛选治疗骨质疏松症的方剂103首,骨性关节炎的方剂106首,分析得到治疗骨质疏松症和骨性关节炎的常用药物、药对及药物组合,并进行了比较。研究表明中医药治疗骨质疏松症和骨性关节炎的用药规律有一定的相似性,均以补肾活血通络为治则治法,但两者的具体用药侧重点存在差异,即骨质疏松症的治疗以补肾为主,佐以活血,而骨性关节炎的治疗以活血通络止痛为主,佐以补肾。该研究结果对骨质疏松症和骨性关节炎的临床用药和新药研发具有一定的指导意义和参考价值。
This paper collected the traditional Chinese medicine（ TCM） prescriptions of osteoporosis and osteoarthritis from CNKI to set up database and used TCM inheritance system to analyze the composing principles in prescriptions. We collected 103 and106 prescriptions for osteoporosis and osteoarthritis respectively,then analyzed inherent principles between herbs in prescriptions by using the TCM inheritance system,and obtained the frequency of each herb,and drug combinations of two diseases’ prescriptions. The result showed that the principles in TCM prescriptions of osteoporosis and osteoarthritis are similarities,such as tonifying kidney and invigorating the circulation of blood,but differences of the specific drugs. That is to say,tonifying kidney is the main method of osteoporosis treatment,however,invigorating the circulation of blood is the main method of osteoarthritis treatment.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2014年第16期3172-3175,共4页
China Journal of Chinese Materia Medica
基金
中央级公益性科研院所基本科研业务费专项(ZZ070830)
关键词
骨质疏松症
骨性关节炎
中医传承辅助平台
中医方剂
osteoporosis
osteoarthritis
traditional Chinese medicine inheritance system
traditional Chinese medicine pre-scriptions
