摘要
[目的]观察六味地黄汤联合西药治疗原发性骨质疏松症疗效。[方法]使用随机平行对照方法,将68例住院患者按就诊先后顺序随机分为两组。对照组34例鲑降钙素,50IU/次,1次/d,1周后改为1次/周,100IU/次,皮下注射;碳酸钙D3,1片/次,1次/d。治疗组34例六味地黄汤(熟地15g,山药、山茱萸各12g,茯苓、泽泻、牡丹皮、车前子、牛膝、黄柏各10g,萆薢15g),1剂/d,水煎200mL,早午晚三次温服;西药治疗同对照组。连续治疗1周为1疗程。观测临床症状、骨密度、疼痛分级、不良反应。治疗4疗程,判定疗效。[结果]治疗组显效16例,有效15例,无效3例,总有效率91.18%。对照组显效10例,有效14例,无效10例,总有效率70.59%。治疗组疗效优于对照组(P<0.05)。两组骨密度、疼痛评分均有改善(P<0.01),治疗组优于对照组(P<0.01,P<0.05)。[结论]六味地黄汤联合西药治疗原发性骨质疏松症,疗效满意,无副作用,值得推广。
[ Objective ] To observe the Six Ingredient Rehmannia Decoction Combined with western medicine in the treatment of primary osteoporosis treatment. [ Method ] Using randomized controlled methods, 68 eases of hospitalized patients according to visiting sequence were randomly divided into two groups. A control group of 34 eases Saleatonin Injection, 50IU/, 1 /d, 1 weeks after the end of 1 times per week, 100IU/ times, subcutaneous injection;Calcium Carbonate and Vitamin D3 Tablets, l tablets each time, 1 times / d. The treatment group of 34 eases of Six Ingredient Rehmannia Decoction （Radix Rehmanniae 15g, yam,Cornus 12g, Poria, Alisma, Plantago, Cortex Moutan, Achyranthes bidentata, Huang Baige 10g, Bixie 15g ）, 1 doses of/d, water simmer in water 200mL, BLD three clothes;western medicine treatment with the control group. Continuous treatment for 1 weeks as 1 course of treatment. Observation of clinical symptoms, bone mineral density, grading of pain, adverse reaction. 4 courses of treatment, the curative effect. [ Result ] The treatment group, 16 cases had marked effect, 15 cases were effective, 3 had no effect, the total effective rate was 91.18%. Control group 10 cases were markedly effective, effective 14 cases, 10 cases were invalid, the total effective rate was 70.59%. The treatment group curative effect is better than that of control group （ P 0.05 ） . Two groups of bone mineral density, pain score were improved （P 〈 0.01 ）, the treatment group is better than that of control group （ P 〈 0.01, P 〈 0.05 ） . [ Conclusion ] The six tastes glutinous rehmannia decoction combined with western medicine in the treatment of primary osteoporosis, satisfied with the effect, no side effect, is worth promoting.
出处
《实用中医内科杂志》
2014年第7期92-94,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
原发性骨质疏松症
六味地黄汤
鲑降钙素
碳酸钙D3
骨密度值
疼痛分级
中西医结合治疗
随机平行对照研究
Primary osteoporosis
Rehmanniae Decoction of six ingredients
Salmon calcitonin
Calcium carbonate D3
Bone density
Pain grading
Integrated traditional Chinese and Western medicine therapy
Randomized parallel controlled study
