摘要
目的观察高压氧联合神经节苷脂及运动疗法治疗新生儿缺氧缺血性脑病(HIE)的临床疗效。方法新生儿HIE 209例,按入院先后顺序分为观察组和对照组,对照组104例给予常规药物综合治疗,观察组105例在常规药物综合治疗基础上加用高压氧联合神经节苷脂、运动疗法,分别于治疗3个月、6个月测评行为能力、被动肌张力、主动肌张力和原始神经反射等指标以评价疗效。结果治疗3个月、6个月时观察组疗效均优于对照组(P<0.05)。结论在常规药物综合治疗基础上,应用高压氧联合神经节苷脂、运动疗法治疗HIE安全、有效。
Objective To observe the clinical efficacy of hyperbaric oxygen combined with ganglioside and exercise therapy on the treatment of neonatal hypoxic-ischemic encephalopathy（ HIE）. Methods Two hundred and nine cases of neonatal HIE were randomly divided into observation group and control group according to the order of hospitalization. The 104 cases in the control group were given the conventional comprehensive drug therapy,while the105 cases in the observation group were treated with hyperbaric oxygen combined with ganglioside and exercise therapy on the basis of conventional comprehensive drug therapy. The behavior ability,passive muscle tension,initiative muscle tension,original nerve reflex and other indicators were evaluated 3 and 6 months after treatment,respectively. Results The curative effects of observation group were superior to those of control group 3 and 6 months after treatment（ P〈0.05）. Conclusion Hyperbaric oxygen in combination with ganglioside and exercise therapy based on the comprehensive drug therapy is safe and effective for the treatment of HIE.
出处
《广西医学》
CAS
2014年第9期1243-1245,共3页
Guangxi Medical Journal
基金
广西贺州市科学研究与技术开发计划项目(1304015)
关键词
缺氧缺血性脑病
高压氧
神经节苷脂
运动疗法
新生儿
Hypoxic-ischemic encephalopathy
Hyperbaric oxygen
Ganglioside
Exercise therapy
Newborns
