摘要
目的观察温针治疗腰椎间盘突出症的临床疗效及对血IL-1a、CGRP的干预作用,比较温针及单纯针刺的疗效差异。方法将60例腰椎间盘突出症患者随机分为针刺组和温针组,每组30例。两组均取双侧肾俞、夹脊穴及患侧环跳、委中、阿是穴,每日1次,10次为1疗程。另设健康对照组15例。观察各组治疗前后下腰痛评分标准(JOA评分)及血CGRP、IL-1a浓度变化情况。结果温针组和针刺组治疗后JOA评分与同组治疗前比较,差异均具有统计学意义(P<0.01)。温针组治疗后JOA评分及改善指数与针刺组比较,差异均具有统计学意义(P<0.05)。温针组和针刺组治疗前血浆IL-1a及CGRP水平与健康对照组比较,差异均具有统计学意义(P<0.01,P<0.05)。温针组和针刺组治疗后血浆IL-1a及CGRP水平与同组治疗前比较,差异均具有统计学意义(P<0.01)。温针组治疗后血浆IL-1a水平与针刺组比较,差异具有统计学意义(P<0.05)。温针组总有效率为96.7%,针刺组为83.3%,两组比较差异具有统计学意义(P<0.01)。结论针灸治疗可能通过降低CGRP及IL-1a浓度发挥镇痛效应,温针在提高患者痛阈、改善腰椎功能方面较单纯针刺疗效更加显著。
Objective To observe the clinical efficacy of warm needling in treating lumber intervertebral disc herniation （LIDH） and its effect on blood IL-1a and CGRP,and to compare the efficacy difference between warm needling and simple acupuncture.Methods Sixty LIDH patients were randomized into an acupuncture group and a warm needling group,30 in each group.In the two groups,bilateral Shenshu （BL 23） and Jiaji （EX-B 2）,as well as Huantiao （GB 30）,Weizhong （BL 40）,and Ashi points on the affected side were treated,once per day,10 times as a treatment course.Another healthy control group with 15 subjects was also developed.The Japanese Orthopaedic Association Scores （JOA） for lower back pain and the contents of blood IL-la and CGRP were observed before and after intervention.Results The JOA scores were changed significantly after intervention in both warm needling group and acupuncture group （P＜0.01）.After intervention,there were significant differences in comparing JOA score and improvement index between the two groups （P＜0.05）.Before intervention,the blood plasma IL-1a and CGRP levels in the warm needling and acupuncture groups were markedly different from those in the healthy control group （P＜0.01,P＜0.05）.The blood plasma IL-1a and CGRP levels were significantly changed after intervention in the warm needling group and acupuncture group （P ＜ 0.01）.After intervention,there was a significant difference in comparing the blood plasma IL-1 a level （P ＜0.05）.The total effective rate was 96.7％ in the warm needling group versus 83.3％ in the acupuncture group,and the difference was statistically significant （P ＜0.01）.Conclusion It＇s plausible that acupuncture plays the analgesic effect via descending the IL-1a and CGRP levels,and warm needling has a more remarkable therapeutic efficacy in enhancing the pain threshold and improving lumbar vertebral function than simple acupuncture.
出处
《上海针灸杂志》
2014年第7期662-664,共3页
Shanghai Journal of Acupuncture and Moxibustion
基金
2011年度湖南省中医药科研计划项目(201188)
关键词
针灸疗法
温针疗法
椎间盘移位
腰
CGRP
IL-1A
Acupuncture-moxibustion
Needle warming therapy
Intervertebral disc displacement, lumbar
CGRP
IL-1a
