摘要
目的了解本院尿路感染病人最常见病原菌大肠杆菌耐药特点,为临床合理治疗提供依据。方法2008年1月—2012年12月,我院确诊并有完整病原学资料的大肠杆菌尿路感染病人602例,其中住院病人368例,门诊病人234例。对门诊与住院病人大肠杆菌耐药率、超广谱β-内酰胺酶(ESBLs)检出率进行比较。结果对绝大部分抗生素住院病人耐药率明显高于门诊病人;住院病人大肠杆菌ESBLs检出率远远高于门诊病人。对大肠杆菌历年耐药率较低的药物依次为:碳青酶烯类、丁胺卡那霉素、耐酶青霉素、头孢西丁。结论门诊与住院病人大肠杆菌耐药率和ESBLs检出率有明显差异,本研究药物敏感性分析结果为临床治疗用药提供了参考。
Objective To understand the characteristics of drug resistance in E.coli-the most common pathogenic bacteria seen in patients with urinary tract infection in our hospital-and provide reference for a rational therapy. Methods From Jan.2008to Dec.2012,602patients with urinary tract infection caused by E.coli were confirmed in our hospital,of whom,368were hospitalized,and 234treated as outpatients.The resistance of E.coli and the detection rate of ESBLs were compared. Results The resistant to vast majority of antibiotics in hospitalized patients was higher than that of outpatients;and the detection of E.coli ESBLs was higher as well.The lower drug resistant rates of E.coli,over the years,to antibiotics were in order of carbapenem,amikacin,penicillinase-fast penicillin and cephalosporin cefoxitin. Conclusion The differences between inpatients and outpatients were significant in terms of drug resistant rate of E.coli and detection rate of ESBLs.The analysis of drug sensitivity of this paper has provided a reference for clinical therapy.
出处
《青岛大学医学院学报》
CAS
2014年第4期357-359,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
泌尿道感染
大肠杆菌
抗药性
细菌
urinary tract infections
Escherichia coli
drug resistance
bacterial
