摘要
[目的]观察逍遥散联合美沙拉嗪肠溶片治疗溃疡性结肠炎疗效。[方法]使用随机平行对照方法,将80例门诊患者按随机数字表法分为两组。对照组40例美沙拉嗪肠溶片1g/次,5次/d。治疗组40例逍遥散(炙甘草7g,柴胡16g,枳壳14g,党参22g,木香16g),1剂/d,水煎200mL,早晚温服;西医治疗同对照组。连续治疗12d为1疗程。观测临床症状、结肠黏膜状态、C-反应蛋白(CRP)、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈22例,有效16例,无效2例,总有效率95.00%。对照组痊愈15例,有效12例,无效13例,总有效率67.50%。治疗组疗效优于对照组(P<0.05)。两组CRP值均有改善(P<0.01),治疗组优于对照组(P<0.01)。[结论]逍遥散联合美沙拉嗪肠溶片治疗溃疡性结肠炎疗效显著,值得推广。
[ Objective ] Xiaoyaosan joint mesalazine treatment of ulcerative colitis enteric-coated tablets. [ Method ] Random parallel control method, 80 outpatients were randomly divided into two groups. A control group of 40 patients mesalazine enteric-coated tablets lg / day, 5 times / d. Treatment group of 40 patients Xiaoyaosan (Zhigancao 7g, Bupleurum 16g, Fructus 14g, Codonopsis 22g, woody 16g), 1 close/d, decoction 200mL, sooner or later, warm clothes;Western medicine with the control group. 12d is a continuous course of treatment. Observation of clinical symptoms, CRP value, adverse reactions. A course of treatment to determine efficacy. [ Results ] The treatment group cure 22 cases, 16 cases effective, 2 cases noneffective, the total efficiency of 95.00%. The control group cure 15 cases, 12 cases effective, 13 cases noneffective, the total efficiency of 67.50%. Treatment group than the control group ( P 〈0.05 ) . CRP values were improved in both groups ( P 〈0.05 ), the treatment group than the control group ( P 〈0.05 ) . [ Conclusion ] Xiaoyaosan mesalazine enteric-coated tablets combined treatment of ulcerative colitis significant effect, worthy of promotion.
出处
《实用中医内科杂志》
2014年第5期85-87,共3页
Journal of Practical Traditional Chinese Internal Medicine