摘要
目的：探讨糖尿病前期患者餐后2h血糖水平与抑郁、焦虑、述情障碍、应对方式、人格等心理因素的相关性.方法：选取符合美国糖尿病协会糖尿病诊疗指南中糖尿病前期诊断标准[7.8 mmol/L≤餐后2h血糖（P2h-PG） ＜11.1 mmol/L]的门诊患者440例,使用自评抑郁量表（SDS）、焦虑自评量表（SAS）、多伦多述情障碍量表（TAS）、特质应对方式问卷（TCSQ）、简式大五人格问卷（NEO-FFIR）评估其抑郁症状、焦虑症状、述情障碍、应对方式及人格特点.结果：患者P2h-PG水平与SDS得分（40.0±8.0）、SAS得分（54.7±10.9）、TAS得分（68.2±9.7）、TCSQ消极应对得分（30.4±7.1）和NEO-FFI-R神经质得分（3.0±0.6）正相关（r=0.13～0.24;均P＜0.01）.多元线性回归分析显示,P2h-PG水平与SDS得分呈正向关联,与NEO-FFI-R谨慎性得分负向关联（标准化β=0.21、-0.18;均P＜0.01）;SDS得分与SAS、TAS得分正向关联,与TCSQ积极应对得分负向关联（标准化β=0.51、0.13、-0.13;均P＜0.01）;SAS得分与SDS得分、TAS得分、NEO-FFI-R神经质得分和谨慎性得分正向关联,与NEO-FFI-R宜人性得分负向关联（标准化β=0.22、0.17、0.14、-0.14、0.13;均P＜0.01）.结论：本研究提示,糖尿病前期患者的血糖升高与抑郁、焦虑、述情障碍、消极应对方式、神经质等心理因素相关,其中与抑郁的相关程度较高.
Objective：To explore the association between plasma glucose levels and psychological factors,such as depression,anxiety,alexithymia,coping style,and personality in patients with prediabetes.Methods：Totally 440 out-patients with the prediabetes （7.8mmol/L ≤ P2h-PG ＜ 11.1 mmol/L） according to Diabetes Treatment Guidelines of American Diabetes Association criteria were selected.The psychological state was assessed with the Self-rating Depression Scale （SDS）,Self-rating Anxiety Scale （SAS）,Toronto Alexithymia Scale （TAS）,Trait Coping Style Questionnaire （TCSQ）,and Neuroticism Extraversion Openness Five-Factor Inventory （NEO-FFI-R）.Results：The plasma levels of P2h-PG were positively correlated with the scores of SDS （40.0 ± 8.0）,SAS （54.7 ± 10.9）,TAS （68.2 ± 9.7）,TCSQ ＂negative coping＂ （30.4 ± 7.1） and NEO-FFI-R ＂neuroticism＂ （3.0 ±0.6） （r =0.13-0.24,Ps ＜0.01）.Multiple linear regression analysis showed the P2h-PG levels were positively associated with scores of SDS and negatively associated with scores of NEO-FFI-R ＂caution＂ （β=0.21,-0.18; P ＜0.01）.The SDS scores were positively associated with the scores of SAS and TAS,but negatively associated with score of TCSQ ＂positive coping style＂（β =0.51,0.13,-0.13; P ＜0.01）.The SAS scores were positively associated with the score of SDS,TAS and NEO-FFI-R ＂neuroticism＂ and ＂caution＂,and negatively associated with the scores of NEO-FFI-R ＂agreeableness＂ （β =0.22,0.17,0.14,-0.14,0.13; P ＜ 0.01）.Conclusion：This study indicates that the increased plasma glucose levels are associated with depression,anxiety,personality,alexithymia and negative coping style in patients with prediabetes,and the association with depression may be significant.
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
2014年第7期486-491,共6页
Chinese Mental Health Journal
基金
十一五国家科技支撑计划项目(2009BAI77B06)
关键词
糖尿病前期
抑郁
焦虑
述情障碍
应对方式
人格
现况调查
impaired glucose regulation
depression
anxiety
alexithymia
personality
coping style
cross-sectional studies
