摘要
目的观察骶管注射地佐辛与新斯的明超前镇痛的临床效果。方法骶管阻滞下行肛肠手术患者120例,按随机数字表法分为Ⅰ、Ⅱ、Ⅲ、Ⅳ四组,每组30例,Ⅰ组骶管注射0.447%罗哌卡因15 ml,Ⅱ组骶管注射0.447%罗哌卡因+新斯的明0.7 mg共15 ml,Ⅲ组骶管注射0.447%罗哌卡因+地佐辛5 mg共15 ml,Ⅳ组骶管注射0.447%罗哌卡因+地佐辛5 mg+新斯的明0.7 mg共15 ml。观察记录各组术后3、6、12、24 h的VAS评分及术后追加镇痛药的时间及用量、肛门排气时间、术后发生恶心呕吐、心动过缓、尿潴留等副作用情况。结果与Ⅰ、Ⅱ两组相比,Ⅲ组和Ⅳ组患者术后24 h内镇痛效果较满意,追加镇痛药的时间明显推迟,且用量明显减少,差异有统计学意义(P<0.05);Ⅱ组和Ⅳ组患者肛门排气时间明显早于Ⅰ组和Ⅲ组,发生尿潴留例数Ⅳ组明显少于其余三组(P<0.05)。结论应用地佐辛与新斯的明超前镇痛可较好地缓解肛肠手术患者术后疼痛,且无明显副作用,值得临床推广。
Objective To observe the preemptive analgesic effects of dezocine and neostigmine in sacral canal injection.Methods One hundred and twenty patients undergoing anorectal surgery through sacral canal anesthesia were randomly divided intoⅠ,Ⅱ,Ⅲ and Ⅳgroups,30 cases in each group.The group I was given 0.447% ropivacin 15 ml;the group Ⅱ was given 0.447% ropivacin ＋ neostigmine 0.7 mg in 15 ml;the group Ⅲ was given 0.447% ropivacin ＋ dezocine 5 mg in 15 ml and the group Ⅳ was given0.447% ropivacin ＋ dezocine 5 mg ＋ neostigmine 0.7 mg in 15 ml.The VAS score,postoperative supplementary analgesic time and dosage of analgesic were recorded at 3,6,12,24 h after anesthesia.Nausea and vomiting,bradycardia,urinary retention and other side effects,and anus exhaust time were noted.Results Compared with the groupⅠ and groupⅡ,the analgesic effect was more satisfactory with longer supplementary analgesic time and less dosage in the group Ⅲ and group Ⅳ.The differences were statistically significant（P〈 0.05）.The anus exhaust time was earlier in the group Ⅱ and group Ⅳ than that in the groupⅠ and group Ⅲ.The cases of urinary retention were significantly fewer in the group Ⅳ than that in the other groups（P〈 0.05）.Conclusion Dezocine and Neostigmine can effectively relieve postoperative pain in patients undergone anorectal surgery without obvious side effects.Thus,it is worthy of clinical promotion.
出处
《实用医院临床杂志》
2014年第4期238-240,共3页
Practical Journal of Clinical Medicine
