摘要
目的探讨小剂量新斯的明硬膜外超前镇痛对妇科病人术后疼痛和胃肠功能的影响。方法60例子宫肌瘤挖除术病人随机分为三组:Ⅰ组病人术前20分钟硬膜外注入新斯的明0.7mg行超前镇痛;Ⅱ组病人关腹时硬膜外注入新斯的明0.7mg;Ⅲ组不用新斯的明镇痛。术后均不用镇痛泵,疼痛较剧时采用哌替定50mg肌注。观察术后2h、6h、12h、24h的疼痛评分、哌替定的使用情况、术后肛门第一次排气时间等。结果Ⅰ组病人24h以内镇痛效果较佳,各时点疼痛评分均明显低于其他两组病人,使用镇痛药的时间明显延迟和次数减少,且无明显副作用(P<0.05)。Ⅰ、Ⅱ组病人术后肛门排气时间明显早于Ⅲ组病人(P<0.05)。结论小剂量的新斯的明行硬膜外超前镇痛可较好地缓解术后疼痛、减少术后镇痛药物的使用,且促进术后胃肠功能的恢复,而无明显的副作用。
Objective To investigate the effect of preemptive analgesia on postoperative pain and gastrointestinal function with low dose of neostignfine through epidural route in gynecological surgery, Methods 60 patients scheduled for hysteromyomectomy surgery were randomly assigned into three groups, Patients in group received neostigmine 0.7mg through epidural route 20 minutes preoperatively, Patients in group received neostigmine 0.7mg through epidural route when operation finished. Patients in group did not receive any neostigmine. Results The Scores of analgesia were lower significantly in group compared with the other two groups within 24h postoperatively, and the time when used mepefidine for postoperative analgesia was postponed markedly and the frequency of use mepefidine was lowest（P〈0.05）, The time of recovering flatus shortened obviously in group and （P〈0.05）. Conclusions Preemptive analgesia with epidural low dose of neostigmine may well help lessen pain and promote gastrointestinal function recovery postoperatively.
出处
《海南医学》
CAS
2006年第9期48-49,共2页
Hainan Medical Journal
关键词
新斯的明
超前镇痛
硬膜外
neostigmine
preemptive analgesia
epidural
