摘要
目的 :研究神经鞘瘤的流行病学和临床治疗情况 ,为防治这一临床常见软组织肿瘤提供参考资料。方法 :统计本院 1993年 3月~ 2 0 0 1年 5月的 8年 2月中住院手术并经过病理学证实的 5 4 3例神经鞘瘤患者的流行病学和治疗学资料 ,按照流行病学、发病率、临床治疗情况分部位、分科进行统计分析。结果 :神经鞘瘤住院率为 2 .85 % ,男女性别比为 1.13 1,身体左右侧发病率之比为 1.73 1。 4 0~ 4 9岁组发病率最高为 2 8.78% ,神经纤维瘤病患者并发神经鞘瘤占神经鞘瘤的 1.6 6 %。颅神经神经鞘瘤发病率占全身发病的 5 0 .4 7% ,颅神经发病中听神经神经鞘瘤又占 6 3.0 6 %。椎管内神经鞘瘤依距离头颅的远近发病率依次下降 ,颈椎 >胸椎 >腰椎 >骶椎。科室统计中 ,神经外科手术时间最长 ,住院时间最长。病理上可见有多种改变如 :坏死、囊性变、液化、细胞丰富等。结论 :神经鞘瘤是一种常见的住院治疗的疾病 ,一次手术治愈率为 97.6 1% ,没有发现恶性变。
Objective: To study the epidemiology and clinical treatment of neurilemoma and provide the reference data to cure this kind of ordinary soft tissue tumor.Methods:From Mar.1993 to May 2001,543 patients diagnosed neurilemoma by pathological examination were in hospital.We counted and analyzed the epidemiology,incidence,treatment and so on of the neurilemoma.Results:Hospitalization rate of neurilemoma was 2.85‰.Male and female ratio was 1.021.Incidence of left and right was not equal 1.73 to 1.The incidence of 40~49 was the highest 28.78%.The incidence of neurofibromatosis in neurilemoma was 1.66%.The incidence of cranial nerves in total body was 50.47% and acoustic nerve in cranial nerves was 63.06%.The incidence of neurilemoma in spinal canal declined gradually from cervical region,thoracic region,and lumbar region to sacral region.Average volume of tumor was 859cm 3 at retroperitoneal neurilemoma and average bleeding was the highest 617cm 3.blood transfusion ratio of neurilemoma in spinal canal was the highest 76.21%.In neurological department,operation time,hospital time and hospital cost were the longest.Much kind of changes could be seen on pathological sample such as necrosis,liquation,cystic degeneration,bundle of cells.Conclusion:Neurilemoma was a common disease in in patients.Cure rate at first operation was 97.61%.There were not any malignant changes except it was diagnosed at first..
出处
《中国矫形外科杂志》
CAS
CSCD
2002年第7期658-661,共4页
Orthopedic Journal of China