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早期乳腺癌保乳手术226例回顾性分析 被引量:6

Retrospective analysis of conservative surgery in 226 cases of early breast cancer
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摘要 目的分析乳腺癌保乳手术后的疗效及美容效果,探讨影响其局部复发的高危因素。方法选取我院2000年1月到2007年12月同意接受乳腺癌保乳手术的226例患者为研究对象。术后给予放、化疗,并进行长期随访。结果全组3年和5年的总存活率分别为97.5%、96.1%,全组3年和5年的无病存活率分别为93.5%、91.2%;16例(7.1%)患者出现远处转移,8例(3.5%)患者出现同侧乳腺肿瘤局部复发;单因素及多因素分析表明,肿瘤大小和切缘远近为影响复发的高危因素。结论乳腺癌的保乳手术从疗效和美容效果上均令人满意,在适应证的选择上,应多注意肿瘤的大小和切缘浸润的情况。 Objective To evaluate the prognosis and cosmetic effect of conservative surgery for breast cancer,and approach the risk factors for the recurrence of conservative surgery.Methods Conservative surgery was performed in 226 patients with early breast cancer,from January 2000 to December 2007,postoperative chemotherapy and radiotherapy were administered.All patients were followed-up for 30 to 106 months.Results The 3 and 5-year total survival rates for all cases were 97.5% and 96.1%,The 3 and 5-year disease free survival rates were 93.5% and 91.2%.Of all the cases postoperative relapse was found in 8 local recurrence and metastasis was seen in 16 cases.Single and multiple factor analysis showed that the size of tumour and the cutting edge from the solitary tumour were the risk factors for the recurrence of conservative surgery.Conclusion Prognosis for patients treated with conservative surgery for breast cancer is satisfactory,and the cosmetic effect is excellent.But for the sellection of indication,the size of tumour and the cutting edge must be considered.
出处 《哈尔滨医科大学学报》 CAS 北大核心 2011年第2期178-181,共4页 Journal of Harbin Medical University
关键词 保留乳房手术 乳腺癌 复发因素 breast conservative surgery breast cancer recurrent factor
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