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腹水纤维连接素鉴别良、恶性腹水

ASSAY OF FIBRONECTIN CONCENTRATION IN ASCITES IN DIFFERENTIATING MALIGNANT FROM NONMALIGNANT ASCITES
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摘要 测定62例良、恶性腹水病人的腹水纤维连接素(Fn)、胆固醇(Ch)及总蛋白(TP)浓度,恶性腹水组Fn和Ch浓度明显高于良性腹水组(P<0.01)。以Fn浓度80μg/ml及胆固醇浓度1.036mmol/L作为鉴别良、恶性腹水的临界值,判断符合率分别为85.5%和77.4%,提示检测腹水Fn浓度可用于鉴别诊断良、恶性腹水。 The fibronection (Fn), Cholesterol (Ch) and total protein (Tp) concentration of ascites in 62 patients with malignant or nonmalignant ascites were assayed. The results suggested that both Fn and Ch concentration in malignant ascites group were significantly higher than those of nonmalignant group (P< 0.01) .When a cutoff concentration of either Fn (80μg/ml) or Ch (1.036mmol/L) was set up, the accuracy of differential diagnosis in two groups of ascites ran as high as 85.5% (Fn) and 77.4% (Ch) respectively.It indicates that to measure the Fn concentration of ascites can be regarded as an important supplementary index in differentiating malignant from nonmalignant ascites.
出处 《湖南医科大学学报》 CSCD 1989年第3期283-285,共3页 Bulletin of Hunan Medical University
关键词 纤维连接素 腹水 蛋白 胆甾醇 fibronectin cholesterol proteins ascites diagnosis
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参考文献1

  • 1张广森,凌柱三,易玉良,唐中华.病理状态下脾脏对血浆纤维结合蛋白及vWFAg含量影响及机制[J]临床血液学杂志,1988(03). 被引量:1

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