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平喘化痰、清热活血法治疗过敏性哮喘儿童嗜酸细胞增多的临床研究

Clinical observation of the method of relieving asthma and dispersing phlegm with clearing away heat and promoting blood circulation in treating the eosinophilic granulocyte increasing caused by allergic asthma in children
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摘要 目的 观察平喘化痰、清热活血法治疗过敏性哮喘儿童嗜酸细胞 (EOS)增多的临床疗效。方法  5 2例过敏性哮喘儿童随机分为 2组 ,治疗组 2 6例用平喘化痰、清热活血法治疗 ,对照组 2 6例用西医治疗。治疗前、治疗中每 2周和治疗结束时分别抽外周静脉血测EOS ,同时治疗前后各测 1次肺功能。 2组疗程均为 45日。结果 治疗组治疗后第 2、4、6、8周末EOS与治疗前比较均有显著性差异 (P <0 .0 5 ) ,对照组治疗后第 2、4、6周末EOS与治疗前比较均无显著性差异 (P >0 .0 5 )。 2组治疗后用力呼气 1秒率 (FEV1 % )、呼气峰流速 (PEF)与本组治疗前比较有显著性差异 (P <0 .0 5 ) ,2组间治疗前后无显著性差异 (P >0 .0 5 )。结论 平喘化痰、清热活血法治疗过敏性哮喘儿童EOS增多疗效确切 。 Objective To observe the therapeutic effect of relieving asthma and dispersing phlegm with clearing away heat and promoting blood circulation on eosinophilic granulocyte (EOS) increasing caused by allergic asthma in children. Methods 52 children with allergic asthma were randomly divided into two groups, 26 patients in treatment group were treated by relieving asthma and dispersing phlegm with clearing away heat and promoting blood circulation; the other 26 patients in control group were treated by western medicine. The EOS in venous blood at the beginning ,in the middle period and at the end of treatment was tested at two-week interval , at the some time the liver function of patients was tested before and after treatment, with a treatment course of 45 days for both groups. Results There were significant differences in EOS at the weekend of 2,4,6,8 weeks in treatment group after treatment, compared with that before treatment (P<0.05);there were no significant differences in EOS at the weekend of 2,4,6,8 weeks in control group after treatment, compared with that before treatment (P>0.05). There were significant differences in the FEV1% and PEF after treatment, compared with that before treatment for both groups(P<0.05);there were no significant differences between the two groups before and after treatment(P>0.05). Conclusion The method of relieving asthma and dispersing phlegm with clearing away heat and promoting blood circulation is effective in treating eosinophilic granulocyte increasing caused by allergic asthma, which can improve obviously the liver function.
作者 李国荣
出处 《河北中医》 2002年第5期329-330,共2页 Hebei Journal of Traditional Chinese Medicine
关键词 中医药疗法 平喘化痰 清热活血法 治疗 过敏性哮喘 儿童 嗜酸细胞增多 临床研究 Allergic asthma Eosinophilic granulocyte Relieving asthma and dispersing phlegm with clearing away heat and promoting blood circulation
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