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The management of patients with the short bowe syndrome 被引量:11

The management of patients with the short bowe syndrome
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摘要 The surgeon is invariably the primary specialist involvedin managing patients with short bowel syndrome. Becauseof this they will play an important role in co-ordinating themanagement of these patients. The principal aims at theinitial surgery are to preserve life, then to preserve gutlength, and maintain its continuity. In the immediatepostoperative period, there needs to be a balancebetween keeping the patient alive through the use of TPNand antisecretory agents and promoting gut adaptationwith the use of oral nutrition. lf the gut fails to adaptduring this period, then the patient may require therapywith more specific agents to promote gut adaptation suchas growth factors and glutamine. lf following this, thepatient still has a short gut syndrome, then the principaloptions remain either long term TPN, or intestinaltransplantation which remains a difficult and challengingprocedure with a high mortality and morbidity due torejection. The surgeon is invariably the primary specialist involved in managing patients with short bowel syndrome.Because of this they will play an important role in co.ordinating the management of these patients.The principal aims at the initial surgery are to preserve life,then to preserve gut length,and maintain its continuity.In the immediate postoperative period,there needs to be a balance between keeping the patient alive through the use of TPN and antisecretory agents and promoting gut adaptation with the use of oral nutrition.If the gut fails to adapt during this period,then the patient may require therapy with more specific agents to promote gut adaptation such as growth factors and glutamine.If following this,the patient still has a short gut syndrome,then the principal options remain either long term TPN,or intestinal transplantation which remains a difficult and challenging procedure with a high mortality and morbidity due to rejection.
机构地区 Department of Surgery
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2002年第1期13-20,共8页 世界胃肠病学杂志(英文版)
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