摘要
为了解醋酸氯己定溶液在高温处理下的稳定性，进行了氯己定含量测定与悬液定量杀菌试验。结果，与未经高温处理的醋酸氯己定溶液相比，经１２１℃压力蒸汽作用２０ｍｉｎ、１１５℃压力蒸汽作用３０ｍｉｎ、１００℃煮沸３０ｍｉｎ，溶液中氯己定含量下降率分别为４、８％、０．４％与０．２％；含氯己定１００ ｍｇ／Ｌ溶液受热处理后与未受热处理者一样，对大肠杆菌作用１ｍｉｎ，对金黄色葡萄球菌与白色念珠菌作用５ ｍｉｎ，杀灭率均为１００％。说明单一醋酸氯己定溶液在高温短时间处理下较稳定。
In order to know the stability of chlorhexidine acetate solution treated with high temper- ature, measurement of chlorhexidine content and suspension quantitative gemicidal test were carried out. The results showed that as compared with the chlorhexidine acetate solution not treated with high temperature, the chlorhexidine contents of the solutions treated with 121℃ autoclaving for 20 min, 115℃ autoclaving for 30 min and 100℃ boiling for 30 min decreased by 4.8%, 0.4% and 0.2% respectively. Same as the chlorhexidine solution not treated with heat, the solution containing chlorhexidine 100 mg/ L treated with heat killed 100% of Escherichia coli after 1 minute contact and 100% of Staphylococcus aureus and Candida albicans after 5 minute contact, indicating that the chlorhexidine acetate solution is stable un- der high-temperature treatment for a short time.
出处
《中国消毒学杂志》
CAS
2002年第1期50-52,共3页
Chinese Journal of Disinfection
