摘要
目的 探讨老年 2型糖尿病患者跟骨定量超声 (QUS)和腰椎骨密度 (BMD)的改变。 方法 采用QUS骨量分析系统检测 94例老年 2型糖尿病患者和 90例健康对照者的跟骨超声传导速度 (SOS)、超声振幅衰减 (BUA)及骨强度指数 (STI) ,用双能X线骨吸收测量仪 (DXA)测定前后位腰椎BMD ,并同时进行了骨生化指标的检测。 结果 2型糖尿病患者BMD(g/cm2 )男性L2 为 0 86 3,低于对照组的 0 931(P <0 0 5 ) ;女性L2 、L2～ 4 分别为 0 82 6和 0 841,均低于对照组 0 90 3和 0 90 5 (P <0 0 1) ;2型糖尿病患者跟骨BUA(dB/MHz)男、女分别为 6 4 6 3、5 1 0 5 ,均低于对照组 71 38和 6 1 76 (P<0 0 1) ,糖尿病组STI男、女分别为 83 12 %和 6 7 6 4% ,低于对照组 91 2 4%和 79 0 3% (P <0 0 5 )。糖尿病组女性SOS(m/s)为 1487 2 8低于对照组 15 0 2 34 (P <0 0 5 )。 结论 老年 2型糖尿病患者跟骨BUA、SOS和腰椎前后位BMD均较正常对照组降低 。
Objective To study the changes and mechanism of calcaneal quantitative ultrasound (QUS)and the bone mineral density( BMD) of AP lumbar spine( L 2-L 4 ) in elderly patients with type 2 diabetes mellitus. Methods Calcaneal broadband ultrasound attenuation ( BUA) ,sound of speed ( SOS ) and stiffness( STI) by QUS ,BMD of the AP lumber spine by dual energy X-ray absorptometry ( DXA ) and some biochemical markers of bone metabolism in elderly patients with type 2 diabetes mellitus ( n=94 )and in healthy control group ( n=90 ) were measured . Results L 2 BMD values(g/cm 2)of male group with type 2 diabetes mellitus was 0.863, which was lower than that of control group ( 0.931, P< 0.05 ). L 2,L 2-4 BMD values ( 0.826 and 0.841 g/cm 2 respectively ) of female group in type 2 diabetes mellitus were lower than that of control groups( 0.903 and 0.905 g/cm 2 respectively, P< 0.01 ); BUA values ( 64.63 dB/MHz for male,51.05 dB/MHz for female) of calcaneal bone in type 2 diabetes mellitus were greatly lower ( P< 0.01 );STI values ( 83.12% for male,67.64% for female ) in type 2 diabetes mellitus were lower than that of control groups ( 91.24%, 79.03% respectively, P< 0.05 ); SOS ( 1487.28 m/s) of female group was lower than that of control group (1502.34 m/s, P< 0.05 ). Conclusions BUA, SOS of calcaneal bone and BMD of the AP lumber spine in elderly patients with type 2 diabetes mellitus are lower than that of control groups,which indicates loss of bone quantity in elderly patients with type 2 diabetes mellitus.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2002年第2期103-105,共3页
Chinese Journal of Geriatrics
