摘要
目的 本文通过对同一个人的跟骨超声声速 (SOS)测量与双能X线吸收法测量腰 2 -4,股骨近端骨密度 (BMD)的临床对比来评价超声骨密度仪测量跟骨的SOS对诊断骨质疏松症的敏感性和与DXA测量BMD的相关性。方法 对 5 2 3名 8～ 87岁健康人群同时采用DXA测量L2 - 4 ,股骨近端 (Neck ,Ward三角 ,Troch)BMD和超声骨密度仪测量左跟骨SOS值并进行相关分析。对 10 0 6名 3～ 87岁健康人群测量左右跟骨的SOS值。结果 SOS与DXA测量BMD的骨峰值 (PBM)均出现在 2 0～ 39岁 ,SOS的PBM男性为 (15 42 83± 2 7 44 )m s ,女性为 (15 31 0 2± 2 9 96 )m s。 40岁以后随着年龄的增加 ,二者均逐渐下降。健康成人中BMD与SOS的相关系数为 0 3～ 0 6 ,骨质疏松患者BMD与SOS的相关系数 (r=0 16～ 0 39)较健康人 (r=0 33～ 0 6 1)低。左右足跟SOS无显著差异 ,DXA的BMD与SOS诊断骨质疏松症 (OP)的符合率为 6 0 %。结论 DXA测量BMD与超声SOS为中等相关。建议在单独使用超声骨密度仪测量SOS来诊断OP时 ,应当参照临床症状和X线的检查全面考虑 ,以免造成漏诊或误诊。
Dual energy x ray absorptiometry(DXA) is a method of measuring the material properties of bone, that is, bone mineral density(BMD), whereas the quantitative ultrasound(QUS) is a method of assessing the mechanical properties of bone by the reflection and attenuation of ultrasound. We evaluated the sensitivity of ultrasound in measuring bone mass by comparing with dual energy x ray absorptiometry. BMD at lumbar spine and proximal part of the femur was measured by DXA and SOS at calcaneus by QUS in 892 subjects of 3 to 87 years in Chengdu. The results showed that SOS peaked at the age of 20 and declined with aging. The peak SOS was (1542 83±27 44)m/s in males and (1531 02±28 96)m/s in females. The correlation coefficients between SOS and BMD were 0 12～0 21 in children and 0 3～0 6 in adults, respectively. The homogeneity rate of the diagnosis of osteoporosis was 60% between DXA and QUS. It was concluded that QUS is used mainly for determining change in bone mass and structure, and DXA mainly for determining change in bone mass; so it had better to use the two methods simultaneously to diagnose osteoporosis and predict the risk of fracture due to osteoporosis.\;
出处
《中国骨质疏松杂志》
CAS
CSCD
2001年第1期42-44,共3页
Chinese Journal of Osteoporosis
关键词
定量超声
双能X线吸收法
骨质疏松
诊断
误诊
Quantitative ultrasound
\ Dual energy X ray obsorptiometry
\ Osteoporosis
