摘要
目的探讨人体跖骨显微硬度的分布特征。方法选取年龄>40岁(性别不限)、既往身体健康、无慢性病史的新鲜冰冻成人尸体3具,来源于河北医科大学解剖学教研室,取出全部右足,剔除软组织。用高精慢速锯于第1~5跖骨基底、跖骨干、跖骨头3个节段,垂直于其长轴进行切割,将骨骼制成若干厚3mm的试样,并用砂纸打磨。应用维氏方法测量标本跖、背、内、外侧不同区域的硬度值,在跖骨头和跖骨基底标本测量松质骨的硬度值,在跖骨干标本测量皮质骨的硬度值。采用50g力加载50s、维持12s标准操作方法测定,同一区域选取5个有效值,全体有效值的平均值作为该部位的硬度值。结果选取45个骨骼区域,共制备45个骨组织试样,测量900个位点。跖骨硬度分布规律基本保持一致,跖骨硬度为(36.35±7.43)HV,其中第三跖骨硬度最大为(38.95±9.01)HV;跖骨干硬度高于跖骨头和跖骨基底,分别为(40.95±6.65)、(34.86±6.68)、(33.25±6.64)HV,差异有统计学意义(F=111.831,P<0.01),而跖骨跖侧、背侧、内侧、外侧的硬度分别为(36.11±7.05)、(36.32±7.49)、(36.69±7.79)、(36.28±7.42)HV,差异无统计学意义(F=0.246,P>0.05)。结论本研究首次报道了人体跖骨显微维氏硬度的分布特征;了解不同部位间的骨显微硬度差异,可帮助骨科医师在该部位骨折内固定手术中,正确选择钢板放置的位置,置钉的密度和方向等,从而获得更加合理的固定效果。本研究结果还可为未来设计硬度和弹性模量与人体生理特点更加接近的接骨板、螺钉、人工骨等奠定了理论基础和数据支持。
Objective To explore the distribution of microhardness of human metatarsal bones. Methods Three fresh frozen bodies with age >40 years old, good health and no chronic history were selected. The soft tissues were removed from the first to fifth metatarsal. These metatarsal bones were dissected and cut perpendicular to the long axis in metatarsal base, metatarsal shaft, and metatarsal head with a low-speed saw and then the bones were made into several 3 mm thick slices and polished by sandpaper. A microindenter fitted with a Vickers indenter point was used to measure the Vickers hardness in the plantar, dorsal, medial and lateral site of bone. The hardness value of the cancellous bone was measured in metatarsal base and head, and the hardness value of the cortical bone was measured in metatarsal shaft. The load was measured by 50 g force for 50 s and maintained for 12 s. Five effective region values were selected in the same area, and the average value of all the effective values was taken as the hardness value of the part. Results Totally, 45 specimens and 900 indentations at different bones and anatomic sites were involved in our reasearch. The hardness distribution of metatarsal bones showed generally same trend among the donors. The total hardness of metatarsals was (36.35±7.43) HV. Among all metatarsal bones, the third metatarsal bone had the largest hardness [(38.95±9.01)HV], and the metatarsal shaft was harder than metatarsal base[(33.25±6.64)HV] and head[(34.86±6.68)HV] .The difference was significant(F=111.831, P<0.01). There was no significant difference in the hardness of plantar site [(36.11±7.05)HV], dorsal site [(36.32±7.49)HV], medial site [(36.69±7.79)HV] and lateral site[(36.28±7.42)HV](F=0.246, P>0.05). Conclusions This study reports for the first time the distribution of microhardness of human metatarsal bone. The difference in bone hardness can benefit the accurate choice of location of plates, the density and direction of screws in the internal fixation of fracture, and obtain a more sc
作者
殷兵
王建朝
李升
张晓娟
刘国彬
刘雅克
吴卫卫
付蕾
张英泽
Yin Bing;Wang Jiangchao;Li Sheng;Zhang Xiaojuan;Liu Guobin;Liu Yake;Wu Weiwei;Fu Lei;Zhang Yingze(Department of Orthopedic, the Third Affiliated Hospital to Hebei Medical University,Orthopaedic Research Institution of Hebei Province, Key Laboratory of Orthopaedic Biomechanics of Hebei Province, Shijiazhuang 050051, China)
出处
《中华解剖与临床杂志》
2018年第6期465-468,共4页
Chinese Journal of Anatomy and Clinics
基金
国家自然科学基金 (8157125、81501934).
关键词
跖骨
硬度试验
维氏硬度
显微硬度
骨骼
Metatarsal bones
Hardness tests
Vickers hardness
Hicrohardness
Human bone
Three-dimensional printing
