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海洋源壳聚糖与海藻酸盐在生物医药领域的应用 被引量:13

Applications of marine-derived chitosan and alginates in biomedicine
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摘要 海洋源生物大分子具有资源丰富、功能独特、生物安全、成本低廉等特点,是生物医用材料研发的优良原料。海洋生物医用材料目前已成为生物医用材料产业的主要分支,符合全球倡导的"绿色产业、低碳经济"的发展大趋势,发展前景极为可观。壳聚糖与海藻酸盐是海洋源生物材料中商业化开发最多的两类材料,在伤口敷料、牙科材料、抗菌处理、药物控释、组织工程等领域均有广泛的应用。本文主要介绍壳聚糖与海藻酸盐的性质及其在生物医药领域的应用,以及作为医用材料发展面临的瓶颈与挑战。 Marine-derived biopolymers are excellent raw materials for biomedical products due to their abundant resources,good biocompatibility,low cost and other unique functions.Marine-derived biomaterials become a major branch of biomedical industry and possess promising development prospects since the industry is in line with the trend of "green industry and low-carbon economy".Chitosan and alginates are the most commonly commercialized marinederived biomaterials and have exhibited great potential in biomedical applications such as wound dressing,dental materials,antibacterial treatment,drug delivery and tissue engineering.This review focuses on the properties and applications of chitosan and alginates in biomedicine.
作者 张婕妤 胡雪丰 李高参 巨晓洁 褚良银 王云兵 ZHANG Jieyu;HU Xuefeng;LI Gaocan;JU Xiaojie;CHU Liangyin;WANG Yunbing(National Engineering Research Center for Biomaterials,Sichuan University,Chengdu 610064,P.R.China;School of Chemical Engineering,Sichuan University,Chengdu 610064,P.R.China)
出处 《生物医学工程学杂志》 EI CAS CSCD 北大核心 2019年第1期164-171,共8页 Journal of Biomedical Engineering
基金 中央高校基本科研业务费专项资助(YJ201626) 四川大学专职博士后研发基金(2018SCU12056)
关键词 壳聚糖 海藻酸盐 生物材料 chitosan alginates biomaterials
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