摘要
目的探讨骨质疏松性椎体压缩骨折(osteoporotic vertebral compression fractures,OVCF)行PKP术后发生骨延迟愈合的相关因素。方法回顾性分析2011-03-2016-03,行PKP手术治疗的238例OVCF患者临床资料,其中发生术后骨折延迟愈合19例,将其作为延迟组,另219例骨折愈合者作为愈合组,统计两组患者的相关指标,并进行组间单因素分析;将组间差异有统计学意义的相关因素进一步进行赋值,予以多因素Logistic回归分析。结果单因素分析显示,骨密度值、椎体内裂隙征、伤椎高度恢复率、骨水泥用量和后凸Cobb角改善度在愈合组与延迟组间呈现显著性差异(P<0.05);愈合组患者术后VAS评分和ODI指数均显著低于延迟组(P<0.05)。多因素Logistic回归分析显示,术前骨密度值偏低、伤椎存在裂隙、伤椎高度恢复率过高,均为导致PKP术后骨折延迟愈合的独立危险因素(P<0.05)。结论 OVCF患者行PKP术后出现骨延迟愈合的相关因素较多,患者骨密度值越低、伤椎高度恢复率越高、术前合并椎体内裂隙征者,均是独立的危险因素。
Objective To investigate the factors associated with delayed bone healing after PKP surgery for osteoporotic vertebral compression fractures(OVCF). Methods The clinical data of 238 patients with OVCF who received surgical treatment of PKP from March 2011 to March 2016 were retrospectively analyzed. Of 238 patients, 19 cases occurred delayed healing after operation were selected as the delay group, another 219 cases with fracture healing were selected as healing group. The relative indicators of two groups were recorded and single factor analysis was performed among the groups;related factors will have a statistically significant difference between groups further assignment, to multi factor Logistic regression analysis. Results Univariate analysis showed that the bone density and vertebral fracture, vertebral height restoration rate, bone cement and kyphosis Cobb angle were improved in healing group, and showed significant differences compared with delay group(P<0.05)., The postoperative VAS score and ODI index in healing group were significantly lower than those in the delay group(P <0.05). Multivariate logistic regression analysis showed that the low preoperative bone mineral density, the fracture of the fractured vertebra and the high recovery rate of the injured vertebra were independent risk factors for delayed fracture healing after PKP(P<0.05). Conclusion There are many factors related to the delayed bone healing after PKP in OVCF patients. The lower the bone mineral density, the higher recovery rate of the injured vertebra, and the preoperative risk of fracture in the vertebral body are independent risk factors.
作者
邱伟
黄朝靖
姜迪
陈浩
QIU Wei;HUANG Chao-jing;JIANG Di;CHEN Hao(Department of Orthopaedics,Ezhou Hospital of Traditional Chinese Medicine,Ezhou,Hubei 436000,China)
出处
《颈腰痛杂志》
2019年第1期46-48,共3页
The Journal of Cervicodynia and Lumbodynia
