摘要
随着生活节奏的加快和社会压力的增大,经前期综合征、抑郁症、焦虑症等情绪障碍类疾病发病率与日俱增,给患者工作、学习及生活造成严重影响;中医称此类疾病为"情志病",认为病位在肝,"肝失疏泄"是其主要病机,中药治疗以平肝和疏肝为主切入调肝机制,其中实验类常用白香丹作为阳性对照,但是白香丹平肝机制却阐释不足,不利于"从现象描述迈向本质阐明",对于更为深入的药理药效研究凸显不足,文章以PMS肝气逆证为切入点,系统分析调肝方药白香丹的平肝机制,有利于深化"肝主疏泄"理论认识,诠释"调肝"内涵。
With the accelerated pace of life and the increase of social pressure,emotional disorders like premenstrual syndrome,depression and anxiety have the increasing incidence,affecting the patients’ work,study and life seriously.TCM calls such diseases as the "emotional disease",which happens in the liver and "liver failing to sooth" is its main pathogenesis.In TCM,Baixiang Dan is commonly used in experiment as a positive control.But the mechanism of Baixiang Dan can not be explained enough,not being conducive to the theroy of "from the description of the phenomenon to the essence of clarification".For more in-depth study of pharmacological efficacy,it is insufficient.This paper taking PMS liver Qi resersing as the evidence,Baixiang Dan’s mechanism is conducive to deepening the "liver dominating soothing" theory understanding,interpretating the connotation of "regulating liver".
作者
高明周
孙亚
夏小雯
孙慧
杨焕新
GAO Mingzhou;SUN Ya;XIA Xiaowen;SUN Hui;YANG Huanxin(Doctoral student,School of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355, Shandong,China;College of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355, Shandong,China;School of Pharmacy,Shandong University of Traditional Chinese Medicine,Jinan 250355,Shandong,China;School of Bioengineering,Qilu University of Technology Shandong Academy of Sciences ,Jinan 250353,Shandong,China)
出处
《辽宁中医杂志》
CAS
2019年第1期129-131,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然基金青年基金(81703941)
山东省青年基金培养基金(ZR2017PH077)
关键词
白香丹
肝主疏泄
调肝方药
平肝机制
Baixiang Dan
liver dominating soothing
regulating liver prescription
mechanism of soothing liver