摘要
目的:观察桃红四物汤合保元汤对冠心病PCI术后气虚血瘀型患者左室收缩功能不全的影响。方法:将52例冠心病PCI术后气虚血瘀型左室收缩功能不全的患者,随机分为治疗组(28例)与对照组(24例)两组,对照组采用正规西药治疗,治疗组在对照组的基础上加用桃红四物汤合保元汤,两组疗程均为1个月。采用多普勒超声心动图检测治疗前后左室收缩功能指标:左室射血分数(LVEF)、左室收缩末内径(LVESD)、左心室短轴缩短率(FS),并观察临床疗效及中医证候疗效。结果:(1)治疗后治疗组的LVEF和FS均明显上升并高于对照组(P<0.05)、LVESD明显降低(P<0.05);(2)治疗组显效17例、有效8例、无效3例,总有效率89.3%;对照组显效6例、有效14例、无效4例,总有效率83.3%;两组显效率的差异具有统计学意义(P<0.05),但总有效率的差异并无统计学意义(P>0.05)。(3)治疗组的中医证候疗效优于对照组,且差异有统计学意义(P<0.05)。结论:桃红四物汤合保元汤对气虚血瘀型冠心病PCI术后左室收缩功能不全的患者具有明显效果。
Objective: To observe the effect of Taohong Siwu decoction and Baoyuan decoction on left ventricular systolic dysfunction in patients with Qi deficiency and blood stasis after PCI.Methods: 52 patients with Qi deficiency and blood stasis type left ventricular systolic dysfunction after coronary heart disease were randomly divided into two groups: treatment group(28 cases)and control group(24 cases).The control group was treated with regular western medicine.In the treatment group,Taohong Siwu decoction and Baoyuan decoction were added on the basis of the control group.The course of treatment was 1 month.Left ventricular systolic function index before and after treatment with Doppler echocardiography: left ventricular ejection fraction(LVEF),left ventricular end systolic diameter(LVESD),left ventricular short axis shortening rate(FS),and observation of clinical efficacy and Chinese medicine syndrome effect.Results: 1.The LVEF and FS of the treatment group increased significantly after treatment and were higher than the control group(P<0.05)and LVESD significantly decreased(P<0.05).2.The treatment group was markedly effective in 17 cases,effective in 8 cases,and ineffective in 3 cases,with a total effective rate of 89.3%.The control group was markedly effective in 6 cases,effective in 14 cases,and ineffective in 4 cases,with a total effective rate of 83.3%.The difference in the efficiency of the two groups was statistically significant(P<0.05).However,the difference in total effective rate was not statistically significant(P>0.05).3.The efficacy of TCM syndromes in the treatment group was better than that in the control group,and the difference was statistically significant(P<0.05).Conclusion: Taohong Siwu decoction and Baoyuan decoction have obvious effects on patients with Qi-deficiency and blood stasis type coronary heart disease after left ventricular systolic dysfunction.
作者
王华
罗玉环
王越
WANG Hua(Lu'an Traditional Chinese Medicine Hospital, Anhui Lu'an 237006, China)
出处
《中医药临床杂志》
2018年第12期2274-2277,共4页
Clinical Journal of Traditional Chinese Medicine
关键词
桃红四物汤
保元汤
益气活血法
冠心病
左室收缩功能不全
Taohong Siwu decoction
Baoyuan decoction
Yiqi Huoxue
Coronary heart disease
Left ventricular systolic dysfunction
