摘要
目的探讨咽喉反流(laryngopharyngeal reflux,LPR)与儿童慢性咳嗽的关系。方法选取2015年9月至2018年3月于首都儿科研究所附属儿童医院就诊的符合慢性咳嗽入组标准的患儿54例,对每例患儿均详细询问病史、体格检查、常规辅助检查及24h咽部pH值监测。所有存在LPR的患儿,均在针对已有病因治疗的基础上,给予饮食指导,必要时同时给予胃动力药物口服治疗,1个月后门诊复查患儿用药、咳嗽等症状情况。结果患儿男31例,女23例,年龄8个月～15岁,中位数年龄7.3岁。24h咽部p H值监测失败0例,7例(12.96%)患有LPR,其中合并咳嗽变异性哮喘2例。治疗1个月后回访发现,4例患儿症状消失,3例患儿症状好转。结论慢性咳嗽患儿中LPR发生率较高,LPR和儿童慢性咳嗽存在一定的相关性,同时治疗LPR有助于慢性咳嗽患儿症状的改善。
Objective To study the relationship between laryngopharyngeal reflux(LPR) and chronic cough in children. Method Children with chronic cough were recruited from September 2015 to March 2018, each patient was given detailed medical history review, physical examination, routine lab examination and 24-hour pH monitoring of pharynx. All the patients with LPR were given diet guidance and etiological treatments, and if necessary, they also were given gastric motility promoting drug. Patients with LPR were followed up and were asked about symptoms and taking medicines in 1 month. Result There were 54 children enrolled in the study, including 31 boys and 23 girls, and age was 8 months to 15 years old (P50 was 7.3). Results showed that no patient failed in 24-hour pH monitoring of pharynx,7 patients had LPR, and the incidence rate was 12.96%. In the patients with LPR, 2 cases were also diagnosed with cough variant asthma. After 1 month, in the patients with LPR, 4 cases recovered, 3 cases improved. Conclusion The incidence rate of LPR in children with chronic cough is high, and the treatment of LPR is helpful to improve the patients’ symptoms. In a word, there is a certain correlation between LPR and chronic cough in children.
作者
常丽
王安琪
曹玲
CHANG Li;WANG An-qi;CAO Ling(Department of Respiratory, Capital Institute of Pediatrics Affiliated Children Hospital, Beijing 100020, China)
出处
《中国医刊》
CAS
2019年第1期50-52,共3页
Chinese Journal of Medicine
基金
北京市属医院科研培育项目(PX2016026)
关键词
慢性咳嗽
咽喉反流
儿童
Chronic cough
Laryngopharyngeal reflux
Children
