摘要
目的分析2013—2017年中国新报告青年学生HIV感染者首次随访及CD4^+T淋巴细胞(CD4)检测情况。方法通过全国艾滋病防治基本信息系统,下载2013年1月1日至2017年12月31日的病例报告卡和随访管理定时数据库。纳入标准为新报告15~24岁且职业为学生的HIV感染者。采用logistic回归模型分析首次CD4检测结果<200个/μl的相关因素。结果2013至2017年新报告青年学生HIV感染者12037例,以男性(97.7%)、19~22岁(65.1%)和汉族(90.5%)为主,感染途径主要为同性传播(82.2%),样本主要来源于检测咨询(46.9%)。2465例(20.6%)在最近3个月发生了无保护肛交,其中1387例(56.8%)有1名性伴,610例(25.0%)有2名性伴,有3名及4名以上性伴的分别有273例(11.2%)和170例(7.0%)。首次CD4检测结果<200个/μl的占11.0%,200~349个/μl的占28.9%。女性(OR=2.09,95%CI:1.51~2.89)、21~22岁年龄组(OR=1.25,95%CI:1.06~1.47)、来源于其他就诊者检测(OR=2.20,95%CI:1.89~2.57)和术前检测(OR=1.36,95%CI:1.07~1.73)较男性、18岁以下年龄组和来源于检测咨询的新报告青年学生HIV感染者首次CD4检测结果<200个/μl的比例更高。结论2013—2017年中国新报告青年学生HIV感染者人数增长显著,晚发现比例较高。女性、21~22岁年龄组,样本来源于其他就诊者检测和术前检测为新报告青年学生感染者首次CD4检测结果<200个/μl的相关因素。
Objective To analyze first follow-up and CD4^+ T (CD4) cell count test of newly reported students HIV cases in China from 2013 to 2017.Methods Data were collected from both Case Reporting Cards and Follow-up Cards from China Information System for HIV/AIDS Control and Prevention between 1st January 2013 and 31st December 2017. The inclusion criteria are 15-24 years old students who were newly diagnosed with HIV infection. Logistic regression model was used to analyze relevant factors of the first CD4 test results less than 200 CD4 cells/μl.Results There were 12 037 newly diagnosed students HIV cases from 2013 to 2017. Most cases were male (97.7%), 19-22 years old (65.1%) and Han ethnicity (90.5%). At the time of diagnosis, the route of HIV infection was most frequently homosexual contact (82.2%). The majority of cases (46.9%) were diagnosed at HIV voluntary counseling and testing (VCT) location. About 2 465 (20.6%) students had unprotected intercourse in the past 3 months, of which 1 387 (56.8%) had 1 sexual partner, 610 (25.0%) with 2 sexual partners, 273 (11.2%) with 3 partners and 170 (7.0%) with more than 4 partners. 11.0% and 28.9% of cases had initial CD4 counts less than 200 cells/μl and 200-349 cells/μl. Compared to the male, younger than 18 years old and diagnosed at VCT location, female (OR=2.09, 95%CI: 1.51-2.89), aged 21 to 22 years (OR=1.25, 95%CI: 1.06-1.47), diagnosed in hospital settings (OR=2.20, 95%CI: 1.89-2.57) and preoperative testing (OR=1.36, 95%CI: 1.07-1.73) had greater proportion of the first CD4 test result less than 200 CD4 cells/μl.Conclusion The number of newly diagnosed students HIV cases significantly increased in past 5 years, and the proportion of late diagnosis was high. Female, aged 21 to 22 years, diagnosed in hospital settings and preoperative testing were related to the first CD4 test result less than 200 CD4 cells/μl.
作者
韩晶
毛宇嵘
汤后林
李健
吴尊友
Han Jing;Mao Yurong;Tang Houlin;Li Jian;Wu Zunyou(National Center for AIDS/STD Control and Prevention,Chinese Center for Disease Control and Prevention,Bering 102206,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2018年第12期1254-1258,共5页
Chinese Journal of Preventive Medicine
