摘要
目的探讨人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染者和艾滋病(acquired immunodeficiency syndrome,AIDS)患者合并阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的临床特征及治疗。方法对我科2015年1月-2018年4月收治的18例HIV/AIDS合并OSAHS患者的病因、临床特征、治疗方法及疗效进行回顾性分析。结果 18例患者中,重度OSAHS 2例,中度OSAHS 7例,轻度OSAHS 9例,病因有慢性扁桃体炎、扁桃体肥大、鼻中隔偏曲、肥厚性鼻炎。经手术治疗后,16例OSAHS症状完全消失,2例症状明显改善。术前扁桃体疾病组和鼻腔疾病组ESS评分为14.54±3.61、15.29±1.60,术后ESS评分分别为8.00±2.65、7.00±1.91,各组内评分差异有统计学意义(P <0.05)。结论 HIV/AIDS合并OSAHS患者在明确诊断、严格把握手术适应证的情况下,实施个体化手术治疗,对改善OSAHS症状疗效肯定。
Objective To explore the clinical feature and surgical treatment of obstructive sleep apnea hypopnea syndrome (OSAHS)in HIV/AIDS patients.Methods The etiology,clinical features,treatment and prognosis of 18 HIV/AIDS patients with OSAHS admitted to our hospital from January 2015 to April 2018 were retrospectively analyzed.Results Of the 18 cases, OSAHS was assessed as severe in 2 cases,moderate in 7 cases,and mild in 9 cases.The causes of disease included chronic tonsillitis,tonsil hypertrophy,deviation of nasal septum,hypertrophic rhinitis.After surgical treatment,the symptoms of OSAHS disappeared completely in 16 cases,and significantly improved in 2 cases.Before the surgery,the ESS score were (14.54±3.61) and (15.29±1.60)in tonsil disease group and nasal disease group,respectively,then it changed to (8.00±2.65),(7.00±1.91)in two groups after surgery,with significant differences compared to before surgery (all P<0.05).Conclusion With definitive diagnosis and strict control of surgical indication,individualized surgical treatment is effective to OSAHS for HIV/AIDS patients.
作者
贾婧杰
鲍诗平
JIA Jingjie;BAO Shiping(Department of Otolaryngology Head and Neck Surgery,Beijing You'an Hospital,Capital Medical University,Beijing 100069,China)
出处
《解放军医学院学报》
CAS
2018年第11期974-977,共4页
Academic Journal of Chinese PLA Medical School
关键词
艾滋病
阻塞性睡眠呼吸暂停低通气综合征
手术治疗
acquired immunodeficiency syndrome
obstructive sleep apnea hypopnea syndrome
operation
