摘要
目的 研制一种新型高分子合成树脂类义齿粘附剂Comfort DA ,测试其主要理化性能。方法 采用正交设计法提出 12种不同配方 ,用单因素方差分析法对影响粘度的各因素进行评判 ,筛选出粘附剂的最佳配比 ;测试Comfort DA的理化性能并与Fittydent义齿稳固剂对比。结果 聚醋酸乙烯酯和纤维素醚的含量对粘附剂粘结抗张强度的影响无统计学意义 (P >0 0 5 ) ,而乙醇与羧甲基纤维素钠所占比例对其粘结强度的影响有统计学意义 (P <0 0 5 ) ,且二者间有交互作用 (P <0 0 5 )。Comfort DA的粘度和剪切应力与Fittydent相近 (P >0 0 5 ) ,而粘结抗张强度优于Fittydent(P <0 0 5 ) ;其酸碱度为中性或弱碱性。结论 Comfort DA义齿粘附剂具有较好的应用前景。
Objective To prepare a new synthetic macromolecular resin class of denture adhesive (named Comfort DA) Methods Twelve different formulae for denture adhesive were designed by orthogonal design Each factor affecting tensile bond strength of adhesive was analyzed by ANNOVA to select the best formula Then the chemical and physical properties, such as tensile bond strength, pH value, and viscosity ,were evaluated and compared with Fittydent in vitro also Results The effect of content of polyvinyl acetate and cellulose ether on tensile bond strength exhibited no statistical significance ( P> 0 05), while ethyl alcohol and CMC Na showed statistical significance and mutual action ( P< 0 05) Results of testing viscosity and shearing stress showed that there was no significant difference between Fittydent and Comfort DA ( P> 0 05), while Fittydent exhibited a significantly lower tensile bond strength than the prepared one ( P< 0 05) The prepared adhesive demonstrated a neutral or slightly basic pH Conclusions The generally favorable in vitro performance of the prepared adhesive (Comfort DA) formulation indicated that it might be efficacious denture adhesive [
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2002年第2期150-152,共3页
Chinese Journal of Stomatology
