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转移性相关基因CD44v6在结直肠癌中的表达意义

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摘要 为探讨CD44v6与结直肠浸润、转移和预后的关系,对165例结直肠癌标本切片,采用CD44v6鼠单克隆抗体进行免疫组化染色(S-P)。结果76例(46.06%)CD44v6阳性,其阳性表达与年龄、性别、肿物大小、部位、组织学类型无关,而与肿瘤是否侵出浆膜层、淋巴结转移、血行转移及3年死亡率呈相关(P<0.005);DukesC期患者3年死亡率57.33%,略高于CD44v6阳性表达组的51.32%(P>0.05)。表明对结直肠癌标本进行CD44v6检测,有助于对结直肠癌患者的淋巴结转移、血行转移情况及预后做出预测。
出处 《中国肛肠病杂志》 2001年第12期7-9,共3页 Chinese Journal of Coloproctology
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