摘要
目的 :观察老年牙周炎患者牙龈组织中 NO水平变化并与健康老年人、慢性成人牙周炎患者、青少年牙周炎患者比较。方法 :采用硝酸还原酶法测量老年牙周炎患者、健康老年人、慢性成人牙周炎患者和青少年牙周炎患者牙龈组织中 NO含量并比较。结果 :老年牙周炎组 NO水平明显低于健康老年人组、慢性成人牙周炎组和青少年牙周炎组 ( P<0 .0 5 )。结论 :由于衰老和牙周炎症的双重作用 ,老年牙周炎患者牙龈组织生成和分泌 NO明显减少 ,导致抗感染和免疫调节功能的改变 ,非特异性免疫功能降低。
砄bjective: To observe NO level in gingival tissue of elderly patients with periodontitis. Methods: 4 mm 3 gingival tissue was obtained during tooth extraction and NO in the tissue of 14 patients aged 65～81 years with periodontitis was measured with nitrate reductase assay. The NO level was compared with that of 9 adult patients (40～58 years old), 6 juveniles patients (25～30 years old) with periodontitis and 9 health elders(65～77 years old).Results:NO(μmol/L)in gingival tissue of elderly patients,health elders,adult patients and juvenile patients were 33.07±12.02,63.53±18.23,55.99±22.40 and 82.15±30.35 respectively.( P <0.05).Conclusion:Aging and inflammation may result in decrease of the production of NO in elderly patients with periodontitis.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2001年第5期397-399,共3页
Journal of Practical Stomatology
