摘要
目的 分析 2型糖尿病患者体质成分与骨密度的相互关系 ,以阐明躯体脂肪含量和肌肉含量在维持骨量中的作用。方法 采用双能X线分析仪 (DEXA)测定 76例 2型糖尿病患者全身各部位的骨密度和肌肉、脂肪含量 ,并根据腰椎骨密度值将病人分为骨质疏松组 19例与非骨质疏松组 5 7例。结果 两组间体重指数、全身及局部脂肪含量无显著差异 (P >0 0 5 ) ,骨质疏松组各部位的骨密度和肌肉含量明显较非骨质疏松组低 (P <0 0 5～ 0 0 1)。糖尿病患者骨密度与全身及局部脂肪含量无明显相关性 ,而与肌肉含量呈显著正相关 (P <0 0 1)。结论
Objective To evaluate the association of body composition with bone mineral density(BMD) in patients with type 2 diabetes mellitus,and to assess the role of fat and lean masses in maintaining the bone content. Methods\ 76 type 2 diabetics with mean age of 63\^8 years,mean duration of disease 6\^9 years,mean HbA 1c 9\^2% were involved in the study.BMD,lean mass,fat mass of total and regional part of the body were determined using dual energy X\|ray absorptiometry (DEXA).The patients were divided into two groups according to BMD of lumbar spine, 2\|4:group 1 with osteoporosis ( n= 19) and group 2 without osteoporosis( n =57). Results\ There were no significant differences in body mass index(BMI) and fat mass between two groups ( P >0\^05).There were significant reductions in BMD and lean mass in regional part of the body in group 1 compared with group 2.There were no correlations between BMD and fat mass in total or regional part of the body ( P >0\^05).There were significant positive correlations between BMD and lean mass in regional part of the body in diabetics( P >0\^01). Conclusion\ The lean mass has a more important effect on BMD than the fat mass in patients with type 2 diabetes mellitus.
出处
《中国骨质疏松杂志》
CAS
CSCD
2001年第3期230-231,234,共3页
Chinese Journal of Osteoporosis
关键词
2型糖尿病
骨密度.
体质成分
脂肪组织
肌肉组织
Diabetes mellitus
Bone mineral density
Body composition
Fat mass
\ Lean mass
