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胃癌患者血清IGF-Ⅱ的表达与幽门螺杆菌感染关系的研究

THE RELATIONSHIP BETWEEN GASTRIC CANCER WITH IGF-Ⅱ AND HELICOBACTER PYLORI INFECTION
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摘要 目的 :探讨胃癌患者血清 IGF- 的含量及与幽门螺杆菌的关系。方法 :应用放射免疫法 (RIA)检测胃癌 35例 ,慢性浅表性胃炎 (CSG) (非萎缩性 ) 76例 ,正常对照 2 0例血清 IGF- 的含量 ,并比较 IGF- 增高与幽门螺杆菌感染与非感染间的关系。结果 :胃癌组血清 IGF- 的含量明显高于慢性浅表性胃炎及正常对照组 (P <0 .0 1) ;低分化腺癌血清 IGF- 含量明显高于高分化腺癌 (P <0 .0 1)。胃癌组与 CSG组幽门螺杆菌感染与非感染间 IGF- 增高率比较差异无显著性 (P >0 .0 5 )。结论 :胃癌患者血清 IGF- 呈过度表达 。 Objective:The relationship between gastric cancer with serum IGF Ⅱ and Helicobacter pylori were investigated Methods:35 cases of gastric cancer,76 cases of non trophic chronic superficial gastritis and 20 cases of control were diagnosed gastroscopically The serum IGF Ⅱ was examined by radioimmunologic method The Hericobacter pylori infection was diagnosed by morphological and biochemistry method Results:The serum IGF Ⅱ level is higher in gastric cancer than in chronic superficial gastritis and normal control(P< 0 01) Conclusion:The serum IGF Ⅱ was significantly higher in patients with gastric cancer It is not associated with Helicobacter pylori infection
出处 《广西医科大学学报》 CAS 2001年第5期609-611,共3页 Journal of Guangxi Medical University
关键词 胃癌 慢性胃炎 IGF-Ⅱ 幽门螺杆菌 含量 放射免疫法 RIA gastric cancer chronic gastritis IGF Ⅱ Helicobacter pylori
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