摘要
目的 探讨HBsAg、CEA与结直肠癌肝转移和预后的关系。 方法 回顾性分析 2所医院 1990年 1月～ 1995年 12月间收治的 5 82例结直肠癌的病例资料 ,并对其HBsAg、CEA进行测定 ,分别观察它们与肝转移和预后的关系。 结果 HBsAg阳性者肝转移率明显低于HBsAg阴性者 (P <0 .0 5 ) ;CEA阳性者与CEA阴性者的肝转移率无显著性差异 (P >0 .0 5 ) ,但CEA阳性者的 5年生存率 ( 31.3 % )明显低于CEA阴性者 ( 84.2 % ) (P <0 .0 1)。结论 结直肠癌很少转移至感染乙型肝炎病毒的肝脏 ,CEA不能作为判断结直肠癌肝转移倾向的指标 。
Objective To investigate the relation of HBsAg?CEA and prognosis and liver metastases in colorectal cancer.Methods 582 patients with colorectal cancinoma were analysed retrospectively.Their HBsAg and CEA were assayed before opertion,then the relation of HBsAg?CEA and prognosis and liver metastases were observed respectively.Results The liver metastases rate of colorectal cancer was significantly lower in the patients with HBsAg(+)than in the patients with HBsAg(-)( P <0.05);it was not different in the patients with CEA(+)and CEA(-)( P >0.05),while the 5 years survival rate of patients with CEA (+)was significantly lower than of patients with CEA(-)(31.3% via 84.2% P <0.01).Conclusion Colorectal cancer may rarely metastasize to the liver infected HBsAg;CEA is not a marker to evaluate tendency of liver metastases,but is one of many markers that are used to evaluate the prognosis of colorectal cancer.
出处
《实用癌症杂志》
2001年第5期501-503,共3页
The Practical Journal of Cancer
