摘要
探讨乙肝表面抗原 (Hbs Ag)、癌胚抗原 (CEA)、Dukes分期与结直肠癌肝转移的关系。回顾性分析 2所医院 1990～ 1995年间收治的 5 82例结直肠癌病例 ,分别观察它们与肝转移之间的关系。发现 Hbs Ag(+)的肝转移率明显低于 Hbs Ag (- )病例 ;Dukes分期较早期的异时肝转移率明显低于较晚期的病例 ;CEA (+)与 CEA (- )病例的肝转移率之间无明显差别 ,但 CEA(+)病例的 5年生存率 31%明显低于 CEA(- )病例的 84%。结直肠癌较少转移至感染乙肝的肝脏。
The relationship between HbsAg, CEA, Dukes staging and liver metastases of colorectal cancer was investigated. 582 patients with colorectal cancinoma from 1990 to 1995 were analyzed retrospectively. The HbsAg and CEA were assayed before operation and the Dukes stagings evaluated during operation. The relationship between HbsAg, CEA or Dukes staging and liver metastases of colorectal cancer were observed respectively. It was showed that the rate of liver metastases of colorectal cancer was significantly lower in the patients with HbsAg(+)or dukes staging A-B than in those with HbsAg(-)or Dukes staging C respectively ( P <0 05 or P <0 01). There was no significant difference between the patients with CEA(+)and CEA(-)( P >0 05), while the rate of 5 year survival of the patients with CEA(+)was significantly lower than that of those with CEA(-)(31 % via 84 %, P <0.01). It was concluded that colorectal cancer metastasized to the liver infected with HbsAg rarely.
出处
《同济医科大学学报》
CAS
CSCD
北大核心
2001年第6期577-579,共3页
Acta Universitatis Medicinae Tongji
