摘要
目的 了解有关小肠隐凹素的研究进展及研究方法。方法 采用文献回顾的方法对有关隐凹素研究的进展进行综述。结果 隐凹素是动物小肠适应肠道有菌环境而产生的一类天然广谱抗生素肽 ,在肠粘膜抗感染防御中具有重要作用。结论 探索隐凹素的作用机理 ,可望找到防止细菌移位及细菌耐药的新途径。
Objective To review the advances a nd research methods on the intestinal cryptdins. Methods The literature in recent years on the s tudy of the cryptdins was reviewed retrospectively. Results Cryptdins were innate broad-spectrum a ntibiotics produced by intestinal Paneth cells in the animal small bowel which adapted to the bacteria circumstance. Conclusion Investigating the acting mechanism o f cryptdins may find a new approach to preventing the bacteria translocation and the bacterial resistance to drugs.
出处
《中国普外基础与临床杂志》
CAS
2001年第6期427-428,F004,共3页
Chinese Journal of Bases and Clinics In General Surgery
