摘要
应用试管-玻片凝集试验测定96例不育男性血清和/或精浆抗精子抗体,阳性率为33.3％,其中血清阳性率31.2％、精浆阳性率为16.3％。血清和精浆两者间的阴性、阳性符合率为75.9％。抗精子抗体对精液量、精子密度和精子的活率等指标无明显影响。并对58例患者血清和精浆标本采用酶联免疫吸附测定法对比测定,结果显示血清和精浆的阴、阳性符合率分别为67.2和74.1％。对56对夫妇分析显示,男方阳性率33.0％,女方阳性率25.0％,其中男女双方均为阳性的发生率为16.1％。夫妇双方有一方阳性者占42.9％。
Antisperm antibodies (AsAb) in the serum and/or seminal plasma of 96 infertile men were determined with the tube-slide agglutination test. 33.3% were found to be positive. Of which, 31.2% were positive in the serum, 16.3% in the seminal plasma. The negative and positive coincidence rate between the serum and the seminal plasma is 75.9%. AsAb do not affect significantly on the volume of semen, the density and viability of spermat-ozoa. The serum and seminal plasma of 58 patients were determined by the tube-slide agglutination test and the enzyme-linked immunosorbent assay. The results showed that the positive and negative coincidence rate of the serum and seminal plasma are 67.2% and 74.1%, respectively. The results of 56 infertile couples showed that the positive rate of AsAb is 33.9% in the husbands, 25.0% in the wives, 16.1% in both of them, 42.9% in one of couples. In addition, the determination methods of AsAb and the relationships between AsAb and clinical infertility were discussed.
出处
《男性学杂志》
CSCD
1991年第3期150-152,159,共4页
关键词
不育症
男性
抗精子抗体
ELISA
Male infertility, Antisperm antibody, Tube-slide agglutination test, Enzyme-linked immunosorbent assay
