摘要
目的 :了解肿瘤化疗后粒细胞缺乏状态患者并发医院感染发生率、易感因素及处理对策。方法及结果 :分析了 5年来 177例肿瘤 (其中主要为血液系肿瘤 )患者。共发生粒缺 3 5 9例次 ,并发医院感染 2 2 1次 ( 61.5 6% ) ,其中败血症 61次 ,肺部及上呼吸道感染 74次 ,口腔、咽部感染 3 8次。共分离出细菌87株 ,G- 杆菌 5 2株 (占 5 9.77% ) ,其中大肠杆菌 2 4株 ;G+ 球菌 2 5株 (占 2 8.74 % ) ,其中金葡菌 15株 ;真菌 10例次。死亡 3 5例 ( 19.77% )。结论 :长期住院、患者处于非无菌环境下、粒细胞缺乏持续时间长是并发感染的主要因素。认为无菌病房的建立、缩短粒缺持续时间 。
Objective: To investigate the nosocomical infection in the agranulocytosis after chemotherapy and its management Methods and Results: 177 cases of neoplasm (most hematological malignant ) were analysed In 359 times of agranulocytosis after chemotherapy,complicated with 221 times nosocomical infections were occured (attacking rate 61 56%), including 61 times septemias, 74 times of lung and upper respiratory tract infections, 38 times of mouth and throat infections.87 strains germs were isolated totally,52 strains were G - bacilli(59.77%),24 of them were colibacilli;25 strains were G + cocci(28.7%),15 of them were staphlococcus aureus,10 cases were fungi.35 cases were died (morbidity was 19.77%).Conclusion:No germ-free environment and persisted agranulocytosis (>1 week) were important susceptable factors All above results suggest that establishing protective environment and shorten time of agranulocytosis are important ways for preventive nosocomical infection.
出处
《江苏预防医学》
CAS
2001年第3期7-8,共2页
Jiangsu Journal of Preventive Medicine
