摘要
作者于1987年10月～1989年1月在西安市某区做了90例肾综合征出血热(HFRS)的病例对照研究。单因素及Logistic回归分析结果表明:皮肤破损、直接接触鼠类、吃过鼠粪尿污染过的食物及口腔粘膜破损为主要危险因素。单因素分析其相对危险度(OR)分别为4.2,4.0,4.1和5.8,上述危险因素相对危险度95%可信限(OR95%CI)下限均大于1,且均有统计学意义(P<0.01)。提示接触传播和经口感染传播可能为疫区人群HFRS的主要传播途径。分层分析结果表明:吃鼠粪尿污染过的食物和口腔粘膜破损两因素可能有协同作用。其他方式的传播作用有待进一步研究。
Using case-control study method, 90 pairs of cases of HFRS and control were investigated at suburbs of Xi' an from October 1987 to January 1989. The results of single variable analysis and Logistic regression analysis indicated that the main risk factors of HFRS infection were:skin damage, direct contact with rodents, eating food contaminated with excrement and/or urine of rodents and oral mucosa damage. The OR of the risk factors mentioned above were 4.2, 4.0, 4.1 and 5.8 respectively. The lower limits of 95% CI of OR were more than 1 and the selected variables had statistical significance (P<0.01), which inferred that the main routes of transmission of HFRS might be:transmission by contact and peroral infection. The results of stratified analysis showed that the two variables between eating food contaminated with excrement and/or urine of rodents and oral mucosa damage might have synergism. The role of the other routes of transmission should be further studied.
出处
《解放军预防医学杂志》
CAS
北大核心
1991年第3期162-166,共5页
Journal of Preventive Medicine of Chinese People's Liberation Army
关键词
肾综合征
出血热
传播
HFRS Case-control study
Route of transmission
Risk factor
Logistic regression analysis
