摘要
概述了巯基乙酸的用途、合成方法 ,研究了二硫化钠法合成巯基乙酸的主要影响因素。实验从硫化钠、硫磺等基本原料出发 ,首先制得二硫化钠溶液 ,然后将二硫化钠同氯乙酸钠反应合成二硫代甘醇酸 ,最后用硫化钠溶液还原得到巯基乙酸。试验探讨了反应物料配比、反应温度、pH值、反应时间等因素对反应转化率的影响 ,实验结果表明该法的转化率可达 96 %左右 ,其具体反应条件如下 :硫化钠∶硫∶氯乙酸钠 (mol) =1.2∶1.4 4∶1.0 0 ,pH值 =7.5,合成二硫代甘醇酸的温度为 35℃ ,时间为
The application and synthesis of thioglycolic acid were reviewed. Thioglycolic acid was synthesized by sodium disulfide method. In the experiment, sodium disulfide was firstly prepared from sodium sulfide and sulfur, and then (SCH 2COONa) 2 was synthesized with ClCH 2COONa and sodium disulfide, in the last step, sodium sulfide aqueous solution, as a kind of reducer, was used to reduce (SCH 2COONa) 2. The effects of reaction temperature, reactant ratio, reaction time, pH value etc., were investigated through experiments. The results showed that the conversion ratio of thioglycolic could reach about 96% under reaction temperature 35℃ and pH value 7.5 for 20 minutes, with a molar reactant ratio of 1.2∶1.44∶1.0(Na 2S∶S∶ClCH 2COONa).
出处
《精细化工中间体》
CAS
2001年第3期21-23,共3页
Fine Chemical Intermediates
