摘要
目的 探讨谷草转氨酶线粒体同工酶 (m AST)与谷草转氨酶细胞浆内同工酶 (s AST)比值在急性心肌梗死(AMI)的早期诊断和AMI后再灌注检测的临床应用价值。方法 采用免疫抑制法检测AMI患者血清中m AST ,观察m ASTs AST比值与其他心肌酶的动态变化。结果 m AST与s AST比值AMI后 6h开始升高 ,然后下降 ,出现再灌注的患者血清中m ASTs AST下降速率 (0 2 8± 0 2 0 ) %明显高于常规治疗和没有出现再灌的患者 (0 11± 0 0 7) %。结论 m ASTs
Objective To explore the clinical application of ratio detection of aspartate aminotransferrase isoenzmyes mitochodrial AST(m AST)cytosolic aspart ate aminotransferrase isoenzmyes in early diagnosis and prediction of successful reperfusion in patients with acute myocardia infarction. Methods The activities of m AST were determined by immunosuppressive method.The ratio of m ASTs AST was compared with CK,CK MB,LDH,s AST for temporal changes. Results The decreased ratio of m ASTs AST in the cases who were successfully reperfused was(0 28±0 20)%that was significantly higher than that of conventionally treated and non reperfused cases(0 11±0 07)%. Conclusion m ASTs AST may be an excellent indicator for AMI in early stage and the decrease ratio of m ASTs AST would predict whether reperfution is successful or not at early stage of AMI.
出处
《中国实验诊断学》
2001年第3期123-124,共2页
Chinese Journal of Laboratory Diagnosis
