摘要
目的 评价SPECT脑血流灌注显像在橄榄桥脑小脑萎缩 (OPCA)诊断中的价值。方法对 2 0例OPCA患者行SPECT脑血流灌注显像和头颅MRI检查 ,并对各项检查结果进行比较。结果OPCA患者的SPECT显像异常表现为脑局部血流低灌注 ,以脑干、小脑及基底节为主 ,也可累及大脑各叶 ;与MRI比较 ,SPECT显示病变范围更广泛 ;SPECT和MRI的异常率分别为 95 %和 75 %。结论SPECT脑血流灌注显像为诊断OPCA提供了新方法 ,灵敏度优于MRI;SPECT与MRI相结合 。
Objective To evaluate the diagnostic value of SPECT rCBF imaging in examining patients with olivopontocerebellar atrophy(OPCA). Methods SPECT rCBF imaging and MRI were performed on 20 patients with OPCA. All the results of two modalities were compared with each other. Results Hypoperfusions of brain were identified in patients with OPCA, especially in cerebellum, brain stem and basal ganglia, and in cerebral lobes in certain cases as well. Compared with MRI, SPECT showed more extensive foci. The positive rates in SPECT and MRI were 95% and 75% respectively. Conclusions SPECT provides a new method for the diagnosis of OPCA. SPECT rCBF imaging is a more sensitive and effective method for OPCA lesion localization comparing with MRI. A combination of these two methods (SPECT and MRI) will improve the positive rate and accuracy for the diagnosis of OPCA.
出处
《中华核医学杂志》
CAS
CSCD
北大核心
2001年第2期87-88,I001,共3页
Chinese Journal of Nuclear Medicine
基金
湖南省科委资助项目! (0 1 942 89 5 )
湖南省卫生厅资助项目! (95 7)
关键词
橄榄体桥脑小脑萎缩
SPECT
脑显像
磁共振成像
Olivopontocerebellar atrophy
Tomography,emission-computed,single-photon
Magnetic resonance imaging
