摘要
目的研究橄榄脑桥小脑萎缩(OPCA)患者椎-基底动脉及局部脑血流(rCBF)的改变。方法对10例OPCA患者行数字减影血管造影(DSA)和单光子发射计算机断层扫描(SPECT)检查,并与对照组(眩晕、短暂性脑缺血发作患者)进行比较。结果OPCA组DSA表现为椎动脉细小5例(50%)、一侧缺如4例(40%)、分支稀疏9例(90%)、动脉晚期脑染色淡10例(100%);SPECT显示小脑及脑干rCBF降低8例(80%);对照组分别为3例(15%)、4例(20%)、4例(20%)、3例(15%)、7例(35%);两组差异有统计学意义(均P<0.01)。结论OPCA患者椎动脉缺如、细小的比率高,椎-基底动脉供血区rCBF减低,提示椎-基底动脉异常可能是OPCA的发病原因。
Objective To investigate the changes of vertebral-basal artery and regional cerebral blood flow(rCBF) in patients with olivopontocerebellar atrophy(OPCA).Methods 10 patients with OPCA were examined by digital subtraction angiography(DSA) and single-photon-emission-computed tomography(SPECT),and compared with the control group(patients with vertigo or transient ischemic attack).Results In OPCA group,there were 5 cases with small vertebral artery(50%),4 cases with single vertebral artery(40%),9 cases with sma...
出处
《临床神经病学杂志》
CAS
北大核心
2008年第5期326-328,共3页
Journal of Clinical Neurology
关键词
橄榄脑桥小脑萎缩
椎-基底动脉
数字减影血管造影
单光子发射计算机断层扫描
局部脑血流
olivopontocerebellar atrophy
vertebral-basal artery
digital subtraction angiography
single-photon-emission-computed tomography
regional cerebral blood flow
